DRSC/TRiP Functional Genomics Resources

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Protein Alignment Git and ARAP3

DIOPT Version :9

Sequence 1:NP_610599.3 Gene:Git / 36122 FlyBaseID:FBgn0033539 Length:731 Species:Drosophila melanogaster
Sequence 2:NP_071926.4 Gene:ARAP3 / 64411 HGNCID:24097 Length:1544 Species:Homo sapiens


Alignment Length:197 Identity:51/197 - (25%)
Similarity:77/197 - (39%) Gaps:41/197 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 DPATPTISTRSKMPRGKSRLQTEVCGDCGAGDPSWASINRGILLCADCCSVHRSLGRHISIVKSL 89
            :..|.|:|......:..|......|.|||:..|.||::|.|:::|..|...||:||..||.|:||
Human   480 EAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSL 544

  Fly    90 RQGN--WEPSVLNFVNSLNAHGANSVWEHHLLDGSTNSTGGKHVPRWRKPTPKDALHP-----TK 147
            :...  |...::.....|....||..|...|                   .|.:.|||     .:
Human   545 KLDTSVWSNEIVQLFIVLGNDRANRFWAGTL-------------------PPGEGLHPDATPGPR 590

  Fly   148 SDFIKAKHVNLTFVLKPSLQDDDDGNGSAGCLEQELSRQLHASVRTSNLETSLRFLV-----QGA 207
            .:||..|: .|....||..|..|         ..:|.:.|.|:|...||..::..|:     :|.
Human   591 GEFISRKY-RLGLFRKPHPQYPD---------HSQLLQALCAAVARPNLLKNMTQLLCVEAFEGE 645

  Fly   208 DP 209
            :|
Human   646 EP 647

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GitNP_610599.3 ArfGap 48..164 CDD:279720 34/122 (28%)
Ank_2 187..279 CDD:289560 8/28 (29%)
ANK <187..270 CDD:238125 8/28 (29%)
ANK repeat 187..213 CDD:293786 8/28 (29%)
ANK repeat 215..247 CDD:293786
ANK repeat 249..279 CDD:293786
GIT_SHD 314..342 CDD:285690
GIT 374..404 CDD:128828
GIT1_C 609..727 CDD:289013
ARAP3NP_071926.4 SAM_Arap1,2,3 4..66 CDD:188889
SAM 12..64 CDD:197735
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 64..147
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 167..194
PH 288..379 CDD:278594
PH1_ARAP 289..381 CDD:270073
PH2_ARAP 398..479 CDD:270074
PH 399..482 CDD:278594 0/1 (0%)
ArfGap 490..606 CDD:279720 35/135 (26%)
PH3_ARAP 676..786 CDD:270076
PH-like <846..894 CDD:302622
RhoGAP_ARAP 909..1084 CDD:239850
RA 1117..1209 CDD:279168
PH5_ARAP 1212..1331 CDD:270079
PH 1241..1325 CDD:278594
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1422..1544
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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