DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Git and arfgap3

DIOPT Version :9

Sequence 1:	NP_610599.3	Gene:	Git / 36122	FlyBaseID:	FBgn0033539	Length:	731	Species:	Drosophila melanogaster
Sequence 2:	NP_991160.1	Gene:	arfgap3 / 402889	ZFINID:	ZDB-GENE-040426-1	Length:	498	Species:	Danio rerio

Alignment Length:	104	Identity:	37/104 - (35%)
Similarity:	54/104 - (51%)	Gaps:	6/104 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SDPATPTISTRSKMPRGKSRLQTEVCGDCGAGDPSWASINRGILLCADCCSVHRSLGRHISIVKS 88
            |:|....||  :.:.|.::....:||.||.|.:||||||..|:.||.||...|||||.|:|.::|
Zfish     2 SEPGKHEIS--AVLKRLRAAAANKVCFDCSAKNPSWASITYGVFLCIDCSGTHRSLGVHLSFIRS 64

  Fly    89 LR-QGNWEPSVLNFVNSLNAHGANSVWEHHLLDGSTNST 126
            .. ..||....|..:.......||:.:..|   |.::|:
Zfish    65 TELDSNWSWFQLRCMQVGGNASANAFFSQH---GCSSSS 100

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Git	NP_610599.3	ArfGap	48..164	CDD:279720	32/80 (40%)
		Ank_2	187..279	CDD:289560
		ANK	<187..270	CDD:238125
		ANK repeat	187..213	CDD:293786
		ANK repeat	215..247	CDD:293786
		ANK repeat	249..279	CDD:293786
		GIT_SHD	314..342	CDD:285690
		GIT	374..404	CDD:128828
		GIT1_C	609..727	CDD:289013
arfgap3	NP_991160.1	ArfGap	10..123	CDD:279720	34/96 (35%)
arfgap3	NP_991160.1	PLN03114	11..486	CDD:178661	33/93 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900