DRSC/TRiP Functional Genomics Resources

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Protein Alignment Git and Agap3

DIOPT Version :9

Sequence 1:NP_610599.3 Gene:Git / 36122 FlyBaseID:FBgn0033539 Length:731 Species:Drosophila melanogaster
Sequence 2:XP_006236000.1 Gene:Agap3 / 362300 RGDID:1310751 Length:1093 Species:Rattus norvegicus


Alignment Length:247 Identity:77/247 - (31%)
Similarity:111/247 - (44%) Gaps:38/247 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 ATPTISTRSKMPRGKSRLQTEVCGDCGAGDPSWASINRGILLCADCCSVHRSLGRHISIVKSLRQ 91
            |..|:.|    .||.|     .|.||.|.:|.|||:|.|.|:|.:|..:||.||.|:|.|:||..
  Rat   846 AVQTVRT----ARGNS-----FCVDCEAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDL 901

  Fly    92 GNWEPSVLNFVNSLNAHGANSVWEHHLLDGSTNSTGGKHVPRWRKPTPKDALHPTKSDFIKAKHV 156
            .:|.|.:|..:.::....|||||| ..|||            :.||.| :|....|..:|:||:.
  Rat   902 DDWPPELLAVMTAMGNALANSVWE-GALDG------------YSKPGP-EACREEKERWIRAKYE 952

  Fly   157 NLTFVLKPSLQDDDDGNGSAGCLEQELSRQLHASVRTSNLETSLRFLVQGADPNY---YHEDKLS 218
            ...| |.|....|           ..|.:||..:|...:|...:..|..|:....   |.:....
  Rat   953 QKLF-LAPLPSSD-----------VPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGR 1005

  Fly   219 TPLHMAAKFGQASQIEMLLIYGADVNALDGNGMTPLELARANNHNTIAERLL 270
            |.||:::........::|:.||.||.:.|..|:|||..||.......|:.|:
  Rat  1006 TALHLSSAMANVVFTQLLIWYGVDVRSRDARGLTPLAYARRAGSQECADILI 1057

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GitNP_610599.3 ArfGap 48..164 CDD:279720 44/115 (38%)
Ank_2 187..279 CDD:289560 23/87 (26%)
ANK <187..270 CDD:238125 22/85 (26%)
ANK repeat 187..213 CDD:293786 5/28 (18%)
ANK repeat 215..247 CDD:293786 8/31 (26%)
ANK repeat 249..279 CDD:293786 8/22 (36%)
GIT_SHD 314..342 CDD:285690
GIT 374..404 CDD:128828
GIT1_C 609..727 CDD:289013
Agap3XP_006236000.1 small_GTPase 309..474 CDD:197466
Centaurin_gamma 311..468 CDD:133303
PH_AGAP 584..827 CDD:241281
PH 587..>648 CDD:278594
ArfGap 855..960 CDD:279720 46/124 (37%)
Ank_2 971..1061 CDD:289560 23/87 (26%)
ANK 971..>1060 CDD:238125 23/87 (26%)
ANK repeat 971..1001 CDD:293786 6/29 (21%)
ANK repeat 1003..1034 CDD:293786 8/30 (27%)
ANK repeat 1036..1061 CDD:293786 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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