Protein Alignment Git and Arfgap2

DIOPT Version :9

• Sequence 1: NP_610599.3
• Gene: Git / 36122
• FlyBaseID: FBgn0033539
• Length: 731
• Species: Drosophila melanogaster
• Sequence 2: XP_006234592.1
• Gene: Arfgap2 / 362162
• RGDID: 1306177
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 552
• Identity: 105/552 - (19%)
• Similarity: 173/552 - (31%)
• Gaps: 198/552 - (35%)

  Fly    41 KSRLQT-----------EVCGDCGAGDPSWASINRGILLCADCCSVHRSLGRHISIVKSLR-QGN 93
            ||.:||           :.|.||||..||||||..|:.||.||..||||||.|:|.::|.. ..|
  Rat     7 KSEIQTLFKRLRAIPTNKACFDCGAKSPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSN 71

  Fly    94 W----------------------EPSVLNFVN---------------------SLNAHGANSVWE 115
            |                      ...:.|..|                     :|..||.: :|.
  Rat    72 WSWLQLRCMQVGGNANATAFFRQHGCLANDANTKYNSRAAQMYREKIRQLGSTALARHGTD-LWI 135

  Fly   116 HHLLDGSTNS---------TGGKHVPRW------------------------RKPTPKDALHPT- 146
            .::....::|         |.....|.|                        .:|.|...|..|
  Rat   136 DNMNSAPSHSPEKKDSDFFTEHTQAPAWDTAATDPSGTQQPALPSESSSLAQPEPGPNTDLLGTS 200

  Fly   147 -----KSDFIKAKHVNLTFVLKPSL------QDDDDGNGS-AGCLEQELSRQLHASV-RTSNLET 198
                 :|.::.||.::.|..||.|:      .....|.|: .|...|::|.|....: |.:.:..
  Rat   201 PQASLESMYLSAKGLSSTRELKSSIIGKKKPAAAKKGLGAKKGLGAQKVSNQSFTEIERQAQVAE 265

  Fly   199 SLRFLVQGADPNYYHEDKLSTPLHMAAKFGQASQIEMLLIYGADVNALDGNGMTPLELARANNHN 263
            .|| ..|.||.....|:.:...:.:|.:                          .|::.|.....
  Rat   266 KLR-EQQAADAKKQAEESMVASMRLAYQ--------------------------ELQIDRKKEEK 303

  Fly   264 TIAERLLDAMYDVTDRIITFLGGKKPDHAS--GRHMIIPDANGADISEQLKIARGKLQLVPNKMF 326
            .:..                |.|||.:.|.  |..::...:....:..::::...:..|......
  Rat   304 KLQN----------------LEGKKREQAERLGMGLVSRSSISHSVLSEMQMIEQETPLSAKSSR 352

  Fly   327 EELVMDLYDEV----------------------DRRECEAIWSTSTLNADHATVPFLPANPFLSA 369
            .:|  ||:|:|                      .|.:.:|.|....:......|......|....
  Rat   353 SQL--DLFDDVGTFASGPPKYKDNPFSLGETFGSRWDSDAAWGMDRVEEKEPEVTISSIRPISER 415

  Fly   370 TRNQGRQKLARFN-------RAEFTG---LLTDVLVDAMRRQNMANLRPMDAPVAGHQSLQSLPY 424
            |.:: |:..:|.:       |.:|.|   :.:|:...          |.:|:.......||.|..
  Rat   416 TTSR-REVESRISGLESSEARQKFAGAKAISSDMFFG----------REVDSEYEARSRLQQLSG 469

  Fly   425 A---NNSMLLGSFE--QGGHDPNLSDDEPIYD 451
            :   ::|.|.|..:  .||...:|.:..|..|
  Rat   470 SSAISSSDLFGDVDGAHGGGTVSLGNVLPTAD 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Git	NP_610599.3	ArfGap	48..164	CDD:279720	46/198 (23%)
		Ank_2	187..279	CDD:289560	10/92 (11%)
		ANK	<187..270	CDD:238125	10/83 (12%)
		ANK repeat	187..213	CDD:293786	6/26 (23%)
		ANK repeat	215..247	CDD:293786	1/31 (3%)
		ANK repeat	249..279	CDD:293786	2/29 (7%)
		GIT_SHD	314..342	CDD:285690	7/49 (14%)
		GIT	374..404	CDD:128828	6/39 (15%)
		GIT1_C	609..727	CDD:289013
Arfgap2	XP_006234592.1	PLN03114	12..484	CDD:178661	97/528 (18%)
		ArfGap	14..117	CDD:214518	29/102 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900