DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Git and cnt5

DIOPT Version :9

Sequence 1:	NP_610599.3	Gene:	Git / 36122	FlyBaseID:	FBgn0033539	Length:	731	Species:	Drosophila melanogaster
Sequence 2:	NP_595897.1	Gene:	cnt5 / 2539865	PomBaseID:	SPBC17G9.08c	Length:	870	Species:	Schizosaccharomyces pombe

Alignment Length:	240	Identity:	58/240 - (24%)
Similarity:	97/240 - (40%)	Gaps:	54/240 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IAPPDLDHSDPATPTISTRSKMPRGKSRLQT--------EVCGDCG-AGDPSWASINRGILLCAD 71
            :..|...:||      |...|..:..|.::|        :.|.||. .....|.:||..::||.|
pombe   651 VTSPSRHNSD------SKEKKQTKSPSLVKTLKEMHSSDQSCADCNTTARVEWCAINFPVVLCID 709

  Fly    72 CCSVHRSLGRHISIVKSLRQGNWEPSVLNFVNSLNAHGANSVWEHHLLDGSTNSTGGKHVPRWRK 136
            |..:|||||.||:.::||....:.|..::.:.:......|.::|..:.|             |:.
pombe   710 CSGIHRSLGTHITKIRSLTLDKFNPETVDLLYATGNSFVNEIYEGGITD-------------WKI 761

  Fly   137 PTPKDALHPTKSDFIKAKHVNLTFVLKPSLQDDDDGNGSAGCLEQELSRQLHASVRTSNLETSLR 201
            ...::  ...:..|:|.|::...|: |.|...|.    :.|.||         |:..|||:.::.
pombe   762 KNFEN--QERRVQFVKDKYLYKRFI-KSSFSHDP----NTGLLE---------SIEHSNLKEAVL 810

  Fly   202 FLVQGADPNYYHE--DKLSTPLHMAAKFGQASQIEMLLIYGADVN 244
            .|..|||.||...  ..|....::.|        |:|.:.||.:|
pombe   811 CLALGADVNYQRAVVKALLKNNYLIA--------ELLTLNGASLN 847

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Git	NP_610599.3	ArfGap	48..164	CDD:279720	28/116 (24%)
		Ank_2	187..279	CDD:289560	17/60 (28%)
		ANK	<187..270	CDD:238125	17/60 (28%)
		ANK repeat	187..213	CDD:293786	10/25 (40%)
		ANK repeat	215..247	CDD:293786	7/30 (23%)
		ANK repeat	249..279	CDD:293786
		GIT_SHD	314..342	CDD:285690
		GIT	374..404	CDD:128828
		GIT1_C	609..727	CDD:289013
cnt5	NP_595897.1	BAR_ArfGAP_fungi	257..455	CDD:153292
		PH-like	513..614	CDD:302622
		PH	532..614	CDD:278594
		COG5347	671..>870	CDD:227651	53/214 (25%)
		ArfGap	674..787	CDD:279720	30/128 (23%)
		ANK repeat	791..821	CDD:293786	13/42 (31%)
		ANK repeat	822..847	CDD:293786	6/32 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810