DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11883 and GOLM1

DIOPT Version :9

Sequence 1:	NP_001097260.1	Gene:	CG11883 / 36121	FlyBaseID:	FBgn0033538	Length:	792	Species:	Drosophila melanogaster
Sequence 2:	NP_057632.2	Gene:	GOLM1 / 51280	HGNCID:	15451	Length:	401	Species:	Homo sapiens

Alignment Length:	292	Identity:	58/292 - (19%)
Similarity:	94/292 - (32%)	Gaps:	85/292 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   500 VELDGRFSRVRTQETNLGNWVCDVVLAAVGADVVILNGGTFRS---------DRVHPVGAFTMGD 555
            :||:||..|                 ||.....|.|....|:.         |::.....|.: :
Human    47 MELEGRVRR-----------------AAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQL-E 93

  Fly   556 LVNVIPMRDPLILLE--VKGKILWQALENGVSAYPKLEGRFPQVSGISFAFDPQAEPGKRIDPQL 618
            .||.:...:..:|:.  ..|:.|.:.|::.:....:..||..|                    .:
Human    94 SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQ--------------------DV 138

  Fly   619 IQVGDEYLNLEQSYKLCVKSYIFMGCDGYTMFKDATVLMDDDACPEL--GITLQNHFKAINSRKC 681
            :|......|||:.:     ||....|  ....|:.     .:.|.|.  .:|.:.: :|:.||..
Human   139 LQFQKNQTNLERKF-----SYDLSQC--INQMKEV-----KEQCEERIEEVTKKGN-EAVASRDL 190

  Fly   682 GQNTKHRQSLVTLSRRHSLVQCLDSMDLDGPSPIRKLSVGHHNKSMDLTHGNSQKMLRRAS---- 742
            .:|...||.|..||.....:|.       ...|..::..|..|     ..|||:......|
Human   191 SENNDQRQQLQALSEPQPRLQA-------AGLPHTEVPQGKGN-----VLGNSKSQTPAPSSEVV 243

  Fly   743 LDDLEQSTCDLAPQLEHRIVMIQNEEHHRQLL 774
            ||...|     ..:.|...:.:.|||..|..|
Human   244 LDSKRQ-----VEKEETNEIQVVNEEPQRDRL 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11883	NP_001097260.1	UshA	202..661	CDD:223808	29/171 (17%)
		MPP_CG11883_N	216..473	CDD:277351
		5_nucleotid_C	494..646	CDD:280945	28/156 (18%)
GOLM1	NP_057632.2	SMC_prok_A	<41..>211	CDD:274009	41/214 (19%)
GOLM1	NP_057632.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..401		27/111 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12546
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950