Protein Alignment CG11883 and NT5E

DIOPT Version :9

• Sequence 1: NP_001097260.1
• Gene: CG11883 / 36121
• FlyBaseID: FBgn0033538
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: NP_002517.1
• Gene: NT5E / 4907
• HGNCID: 8021
• Length: 574
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 140/557 - (25%)
• Similarity: 250/557 - (44%)
• Gaps: 98/557 - (17%)

  Fly   216 LTILHYNDVYN-IESMAE--------TEPVGGAARFATAIKSF--AHLNPLVLFSGDAFSPSMLS 269
            |||||.|||:: :|..:|        :..:||.||..|.::..  |..|.|:|.:||.:..::..
Human    29 LTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWF 93

  Fly   270 TFTQGEQMIPVLNTVGTHCAVFGNHDFDHGLDVLVK-LIKQTEFPWLMSNVVDNETGRPLGGGKI 333
            |..:|.::...:|.:.......|||:||:|::.|:: |:|:.:||.|.:|:   :...||.....
Human    94 TVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANI---KAKGPLASQIS 155

  Fly   334 SHFILHNQISIG--LIGLVEREWLETLPTIDP-NEVTYIDYVEAGNKLARELRNEGCDLIIALTH 395
            ..::.:..:.:|  ::|:|.....||....:| ..:.:.|.:.|......:|:....:.||||.|
Human   156 GLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGH 220

  Fly   396 MRTPNDINLAEKCNGIDIILGGHDHV---------RE---------VTEINGKM--IVKSGTDFQ 440
            .....|..:|:|..|:|:::|||.:.         :|         ||..:|:.  :|::....:
Human   221 SGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGK 285

  Fly   441 QFSVITIERDAANR---EHFTTDVKCFDVTAKIPEDPELKQELSKYAKFIESKLSDVMGVFSVEL 502
            ....:.||.|....   .|....:    :.:.|||||.:|.:::|:...:::..:..:|...|.|
Human   286 YLGYLKIEFDERGNVISSHGNPIL----LNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYL 346

  Fly   503 DGRFSRVRTQETNLGNWVCDVVLAA----------VGADVVILNGGTFRSDRVHPV-----GAFT 552
            ||.....|.:|.|:||.:||.::..          ....:.|||||..||    |:     |..|
Human   347 DGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRS----PIDERNNGTIT 407

  Fly   553 MGDLVNVIPMRDPLILLEVKGKILWQALENGVSAYPKLEGRFPQVSGISFAFDPQAEPGKRI--- 614
            ..:|..|:|......|:::||..|.:|.|:.|..|.:..|.|.||.||...:|...:||.|:
Human   408 WENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKL 472

  Fly   615 ------------DPQLIQVGDEYLNLEQSYKLCVKSYIFMGCDGYTMFKDATVLMDDDACPELGI 667
                        ||         |.:::.||:.:.:::..|.||:.|.|| .:|..|....::.:
Human   473 DVLCTKCRVPSYDP---------LKMDEVYKVILPNFLANGGDGFQMIKD-ELLRHDSGDQDINV 527

  Fly   668 T------LQNHFKAINSR---KCGQNTKHRQSLVTLS 695
            .      ::..:.|:..|   ..|.:.....||:.||
Human   528 VSTYISKMKVIYPAVEGRIKFSTGSHCHGSFSLIFLS 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11883	NP_001097260.1	UshA	202..661	CDD:223808	133/512 (26%)
		MPP_CG11883_N	216..473	CDD:277351	72/294 (24%)
		5_nucleotid_C	494..646	CDD:280945	49/181 (27%)
NT5E	NP_002517.1	UshA	11..532	CDD:223808	133/523 (25%)
		MPP_CD73_N	29..310	CDD:277354	70/287 (24%)
		5_nucleotid_C	339..507	CDD:280945	49/180 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0737
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001036
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810