DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment psq and CG34376

DIOPT Version :9

Sequence 1:	NP_001369078.1	Gene:	psq / 36118	FlyBaseID:	FBgn0263102	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_732741.1	Gene:	CG34376 / 42638	FlyBaseID:	FBgn0085405	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	783	Identity:	179/783 - (22%)
Similarity:	260/783 - (33%)	Gaps:	263/783 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FSLRWNNYQNTMTSVFQQLREDLSFVDVTLSCEHGSLKAHKVVLSACSTYFQKLLLENPCKHPTI 74
            |.|.|.|:|:.:.|.||.|.:....|||||:|:...|.|||:||:.||.|||::...||||||.|
  Fly     5 FKLCWKNFQDNIASGFQNLYDRGDLVDVTLACDGKLLHAHKIVLAICSPYFQEIFTTNPCKHPII 69

  Fly    75 ILPADIIFTDLKTIIDFVYRGEIDVTESELQGLLRTAEQLKIKGLCETAENADDLNDAATATITV 139
            || .|:.|..:..:::|:|:|.::|..:|||..::..:.|:||||      |.:.|.:..::::.
  Fly    70 IL-KDVSFNIMMELLEFMYQGVVNVKHTELQSFMKIGQLLQIKGL------ATNSNSSPGSSVSE 127

  Fly   140 SENIQQAVVGNIVNAAIVPGAPSPSLEQQQQHHQQQQQQQAQEQHQQQQVHAQQQQQQQQQINAA 204
            ..:.|             |.|...|......||..........:.:      ....:.:.|.|:.
  Fly   128 KSSSQ-------------PPAEESSNTNSTNHHNSSTNSNNNSKSE------TDHNESKGQSNSR 173

  Fly   205 LLTQHGVS----------------------SGSVSL-SGQLLSSSAS--GSSGSLAGGQQASQTP 244
            ..:..|.|                      |.|:|: ||:.|..|..  ||.||..||...:.|.
  Fly   174 TTSPGGASRASNDASHLYTSNKRPMPSDFGSDSLSIYSGKQLRRSLKDHGSGGSEGGGGDHADTA 238

  Fly   245 SGLQPTPRKSRLKRSKSPDLSSGGGAGSSGGSSSGSTQQQPQPAHHHHPQTILIQGQNPNSIVSL 309
            :||..:...........|.::.|......||      .::....|||.|  :...|.|..|:.||
  Fly   239 AGLDNSMNSEEFFLPPIPQITMGEQRYDLGG------LKRESDGHHHGP--LSAGGGNSGSVGSL 295

  Fly   310 QQTADGNYIPVSG-------------SGDDSDAEDHEHEHNHGHGHGHGGHTHGHGHSHEHSHDH 361
            ..:|..: .|:..             .|.:|........::.|.|..:...:.|.|...|:.::
  Fly   296 TSSASPS-APIRNPFAPNFMDSFNYYKGGNSSGPSGSSNNSVGPGGVNNNGSVGLGSGAEYPNE- 358

  Fly   362 EHEHKPNKICKTEHSVASPASNSSSASN------------------------------------- 389
              .:.||...|   |.|:.....||.||
  Fly   359 --LYMPNDYSK---SFANHMDIPSSGSNMVMLSTTSLLHGNCVFNRNNTVATQQGMKTYWLCKSY 418

  Fly   390 -----------------NAAGVSGVT-----STGQAIVTQIVVARDGKDTKNMTSLGMGM--NGG 430
                             :|.||...|     ..|.:..:...|:.:...|...:..|..:  .||
  Fly   419 RISMCRARCITHLGRIISATGVHNHTPHMRGGQGSSAPSTASVSGNPAPTPISSQAGYSLTDGGG 483

  Fly   431 LLG--------VPMGFLDFT-PEPPAPSATPVTVTEHVDLSCNPSTDTRDLSNTTEPLDIDNHLA 486
            .||        |...|.:.| |.||.|...||..|.|
  Fly   484 HLGPDLQHGNRVTNMFANQTPPPPPPPPPLPVASTPH---------------------------- 520

  Fly   487 QQIHRLDQSPMHSISHHHTGDESNSNLVQHIKSEVIEAKHLAAQH---HALSQA---------QQ 539
                       |...|||.|....:.||||         |.|..|   |..|.:         .|
  Fly   521 -----------HPHHHHHLGQPLPNLLVQH---------HPAPSHMEQHGSSASLLHNPNLMHLQ 565

  Fly   540 QHAHHQAHQQHQQHQQQQHQQQQQHL--------HAQQLLAQSQLQQQQQ--------------- 581
            ...||...|.||||........|||.        ....||:.:.|||..|
  Fly   566 TPTHHHQQQHHQQHSPHNPPPPQQHNLELGGGSGSGAVLLSPAHLQQSPQSNRSSHSLQAQSPPP 630

  Fly   582 QQQQQQQHHQQQQQQAAAAAAAAGVHGQHGGHVTHADIGGATVMEIDPSQIKHEPGMIITPEIVN 646
            |..::||.|||||||..                     |..|.:..|||          |..::|
  Fly   631 QSVEEQQPHQQQQQQQE---------------------GATTEVTTDPS----------TAHVIN 664

  Fly   647 MMS 649
            .::
  Fly   665 SIT 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
psq	NP_001369078.1	BTB_POZ_BAB-like	34..118	CDD:349624	37/83 (45%)
		HTH_psq	717..>747	CDD:283007
		HTH_psq	767..804	CDD:283007
		HTH_psq	821..866	CDD:283007
		HTH_psq	873..916	CDD:283007
CG34376	NP_732741.1	BTB	20..113	CDD:279045	41/93 (44%)
		BTB	31..115	CDD:197585	39/90 (43%)
		FLYWCH	390..443	CDD:282369	3/52 (6%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I9606
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.020