DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment psq and CG6765

DIOPT Version :9

Sequence 1:	NP_001369078.1	Gene:	psq / 36118	FlyBaseID:	FBgn0263102	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_001261582.1	Gene:	CG6765 / 38971	FlyBaseID:	FBgn0035903	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	804	Identity:	139/804 - (17%)
Similarity:	243/804 - (30%)	Gaps:	287/804 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAVRGHQYFSLRWNNYQNTMTSVFQQLREDLSFVDVTLSCEHGS-----------LKAHKVVLS 54
            |||...|    |:|:::...:.|....|.::..|.||.|...:.|           :.|||.:||
  Fly     1 MAAENYH----LKWDSHLTYLNSSIATLYKNEKFADVVLYSSYNSSGIPSDIPTVGISAHKFILS 61

  Fly    55 ACSTYFQKLLLENPCKHPT----IILPADIIFTDLKTIIDFVYRGEIDVTESELQGLLRTAEQLK 115
            |.|.:|..:....|..:|.    ::||.|:....::.::.::|.||..|:...|..:||..|.||
  Fly    62 ASSQFFATMFETAPITNPNGVLYVVLPPDLSHRAIQILVQYMYSGEATVSNDILNEVLRGGEILK 126

  Fly   116 IKGLCETAENADDLNDAATATITVSENIQQAVVGNI-------------VNAAIVPGAPSPSLEQ 167
            |:|||.|:.:    |...:.::..:.:...::.|::             ...|:.|..|.|....
  Fly   127 IRGLCRTSSS----NGGGSGSVVTTTHHPHSLAGHLHPREASTMYMSNGTRTALPPPPPPPQSTM 187

  Fly   168 QQQ-------------------HHQQQQQQQAQEQHQQQQVHAQQQQQQQQQINAALLTQHG--- 210
            ..|                   ||...........|        ..|||.:.:.|:::.:..
  Fly   188 SAQLQGDLYASKPGGSTRFALDHHHLSSHHSHLNHH--------NPQQQFRGLGASVMPKDSPVI 244

  Fly   211 VSSGSVSLSGQLLSSSASGSSG----------------SLAGGQQASQTPSGLQPTPRKSRLKRS 259
            :.|..::....||:.::|...|                ..|.||..||:    .|.|       .
  Fly   245 IKSPKLAAHTGLLTVASSSKLGISVNKEVAIDPEDKCCFAAPGQLESQS----HPPP-------P 298

  Fly   260 KSPDLSSGGGAGSSGGSSSGSTQQQPQPAHHHHPQTILIQGQNPNSIVSLQQTADGNYIPVSGSG 324
            .:...:.|||.||.|||                       |..|:..:|:......:..|::...
  Fly   299 TTTTTTVGGGGGSVGGS-----------------------GAPPSQPISICTEVGCSSCPLTAGP 340

  Fly   325 DDSDAED----HEHEHNHGHGHGHGG----HTHGHGHSHEHSHD-HEHEHKPNKICKTEHSVASP 380
            ....||.    .|:|..........|    .......:.|.|.| :|..|       .||.|:|.
  Fly   341 GADQAETTLRRTEYEEQALRERNEVGLVFERRLRRESACERSRDYYEAPH-------FEHVVSSR 398

  Fly   381 ASNSSSASNNAAGVSGVTSTGQAIVTQIVVARDGKDTKNMTSLGMGMNGGLLGVPMGFLDFTPEP 445
                                                                      |..||.|
  Fly   399 ----------------------------------------------------------LAATPPP 405

  Fly   446 P---APSATPVTV----------TEHVDLSCNP----------STDTRDLSNTTEPLDID-NHLA 486
            |   ||.:.|.|:          .|..|.|.||          :.:...|::..:|||.. :.:.
  Fly   406 PPQQAPPSHPPTLRHPHNFLTIKQEPTDWSNNPPNASSASNNNNLEELPLASPKQPLDFKMSAVK 470

  Fly   487 QQIHRLDQSPMHSISHHHTGD-----------------ESNSNLVQHI-----------KSEVIE 523
            .:::|...:|......|...|                 |....||:|:           :..::.
  Fly   471 LEVNRDRGTPSEESEEHTLRDYNNFKQLLVCEICQKSFEDTKMLVRHLGTHAGDPTGGTERNLLP 535

  Fly   524 AKHLAAQHHALSQAQQQHAHHQAHQQHQQHQQQQHQQQQQHL----------------------- 565
            :....:...|.|....:.......::.::..||::.....|:
  Fly   536 SSASGSTTSASSNLALRSVKTYVPKKRRRVSQQENNMDHDHVTLLCDLCSTSFDTPAEWVRHMNS 600

  Fly   566 -HAQQLLAQSQLQQQQQQQQQQQQ-----------HHQQQQQQAAAAAAAAGVHGQHGGHVTHAD 618
             |.:..||....::..:|:.||..           .:.|.|.:..::.|....|......::::|
  Fly   601 QHTEIELAMFNSKKDGEQKGQQPPPPPATSSSSTVSNSQMQPKYPSSTATRSTHSLMLHKMSNSD 665

  Fly   619 IGGATVMEIDPSQIKHEPGMIITP 642
            ....|.          .||...:|
  Fly   666 AVATTT----------SPGASTSP 679

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
psq	NP_001369078.1	BTB_POZ_BAB-like	34..118	CDD:349624	29/98 (30%)
		HTH_psq	717..>747	CDD:283007
		HTH_psq	767..804	CDD:283007
		HTH_psq	821..866	CDD:283007
		HTH_psq	873..916	CDD:283007
CG6765	NP_001261582.1	BTB	24..132	CDD:279045	32/107 (30%)
CG6765	NP_001261582.1	BTB	53..130	CDD:197585	24/76 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010