DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment psq and CG3726

DIOPT Version :9

Sequence 1:	NP_001369078.1	Gene:	psq / 36118	FlyBaseID:	FBgn0263102	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster

Alignment Length:	989	Identity:	197/989 - (19%)
Similarity:	292/989 - (29%)	Gaps:	411/989 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QYFSLRWNNYQNTMTSVFQQLREDLSFVDVTLSCEHGSLKAHKVVLSACSTYFQKLLLENPCKHP 72
            |.:.|||..:.:.:.::|.||.:...|.||||:||...::||:|||.||||:|..:|.....:..
  Fly     4 QQYCLRWKYHHSNLQTMFSQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAVLSNYASERD 68

  Fly    73 TIILPADIIFTDLKTIIDFVYRGEIDVTESELQGLLRTAEQLKIKGLCETAENADDLNDAATATI 137
            .||:..|:.|.::|.:|:|:|:|||:|..|.|..||:||:.||||||.|.....|:
  Fly    69 PIIIMKDVTFAEVKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGLAEVTWRDDE--------- 124

  Fly   138 TVSENIQQAVVGNIVNAAIVPGAPSPSLEQQQQHHQQQQQQQAQEQHQQQQVHAQQQQQQQQQIN 202
                                 ..|.|.:...:.|   ...:...|.:.|..: .|.||||||...
  Fly   125 ---------------------DGPPPPMAAAEFH---SPPRSLAESYAQDLI-LQHQQQQQQGPA 164

  Fly   203 AALLTQHGVSSGSVSLSGQLLSSS------------ASGSSGSLAGGQQASQTPSGLQPTPRKSR 255
            |..|..|.        |..||...            :.|..|.|  |:....||
  Fly   165 APPLNLHS--------SAALLERDRERERERDRERLSPGMEGVL--GRMPVMTP----------- 208

  Fly   256 LKRSKSPDLSSGGGAGSSG-GSSSGSTQQQPQPAHHHHPQTILIQGQNPNSIVSLQQTADGNYIP 319
                      ..|.:||:| ||.||.|                          ||:..|     |
  Fly   209 ----------LTGASGSAGVGSVSGGT--------------------------SLEGVA-----P 232

  Fly   320 VSGSGDDSDAEDHEHEHNHGHGHGHGGHTHGHGHSHEHSHDHEHEHKPNKICKTEHSVASPASNS 384
            |                                                     ||
  Fly   233 V-----------------------------------------------------EH--------- 235

  Fly   385 SSASNNAAGVSGVTSTGQAIVTQIVVARDGKDTKNMTSLGMGMNGGLLGVPMGFLDFTPEPPAPS 449
                                                          .||           |....
  Fly   236 ----------------------------------------------FLG-----------PKRKR 243

  Fly   450 ATPVTVTEHVDLSCNPSTDTRDLSNTTEPLDIDNHLAQQIHRLD--QSPMHSISHHHTGDESNSN 512
            ..|            |..|..|:.|..:       |||....|:  |......:.|.|
  Fly   244 GRP------------PLDDAYDVFNVRK-------LAQYAANLEPAQRAYLETARHFT------- 282

  Fly   513 LVQHIKSEVIEAKHLAAQHHALSQAQQQHAHHQAHQQHQQHQQQQHQQQQQHLHAQQLLAQSQLQ 577
                      |...|||  ||.|.|....|.....:|..:|||||.||          |.||:..
  Fly   283 ----------EEPPLAA--HAASMASPPAACPPKQRQRLRHQQQQQQQ----------LLQSESS 325

  Fly   578 QQQQQQQQQQQHHQQQQQQAAAAAAAAGVHGQHGGHVTHADIGGATVMEIDPSQIKHEPGMIITP 642
            .|:|....|...:.:....|.....:.|                      |.::.:.|.|....|
  Fly   326 DQEQPAAGQDWSNLEPNGSATPKLLSDG----------------------DANKQETEGGDESLP 368

  Fly   643 EIVNMMSSG-------------------HMDMYNSDTSEDSMMIANGSPHDQKEPHYTNLDQQHG 688
            .::...||.                   |.......:.||.:......|.:..:| ...::.:|.
  Fly   369 AVLTTASSSGTKKLEKIGERRERHGKLRHARRLYEKSGEDEVDPPKEEPDELPQP-VEEIENEHL 432

  Fly   689 LGGSVCGPGP-------------GGAGGGGGMSGGAGSGSGEKALDALKNQ-----------NMS 729
            :......|.|             ||....||.| |:|:|||......|.|:           |::
  Fly   433 VANRAESPRPTVVIPASFACKYEGGVTAAGGGS-GSGTGSGSLGSSYLINEHGMLMAHEFAPNVA 496

  Fly   730 LTKASAIYGIPSTTLWQRAHRMGIETPKKEGGTKSWNEDALQNALEALRSG--QISANKASKAFG 792
            ...|:|...:.:...                        |:.||.....:|  .:|.:....|..
  Fly   497 SAAATAAVAVAAAAA------------------------AVANASAGNGNGGQDVSGSGTGAAAD 537

  Fly   793 IPSSTLYKIARREGIRLAAPFNAAPTTWTPEDLERALEAIRAGNTSVQKASAEFGIPTGTLYGRC 857
            .|...|            ..::||....|.|:|.:..:.|:..:...:              ||
  Fly   538 YPDIKL------------EDYDAAELRLTNEELSQWQDVIKMDDYLAK--------------GR- 575

  Fly   858 KREGIELSRSNPTPWSEDAMNEALNSVRVGQMSINQAAIHYNLPYSSLYGRFKRGKYDVVANT-S 921
                      .|..|.|......|::::..::.:.:||....:.|.:||||: |..|..:.:. |
  Fly   576 ----------RPQFWEEPFTKRVLDAIKNKRLEMKKAARILGVSYGTLYGRY-REVYGCLKHPYS 629

  Fly   922 GVALLNTSGNTTGS 935
            |.|..| ||:|:.|
  Fly   630 GTAFRN-SGSTSTS 642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
psq	NP_001369078.1	BTB_POZ_BAB-like	34..118	CDD:349624	39/83 (47%)
		HTH_psq	717..>747	CDD:283007	5/40 (13%)
		HTH_psq	767..804	CDD:283007	8/38 (21%)
		HTH_psq	821..866	CDD:283007	6/44 (14%)
		HTH_psq	873..916	CDD:283007	11/42 (26%)
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	45/96 (47%)
		BTB	32..121	CDD:197585	42/88 (48%)
		HTH_psq	587..622	CDD:283007	9/35 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I9675
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	73	1.000	Inparanoid score	I5272
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.160