DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment psq and Btbd18

DIOPT Version :9

Sequence 1:	NP_001369078.1	Gene:	psq / 36118	FlyBaseID:	FBgn0263102	Length:	1170	Species:	Drosophila melanogaster
Sequence 2:	NP_001138572.1	Gene:	Btbd18 / 100270744	MGIID:	3650217	Length:	723	Species:	Mus musculus

Alignment Length:	347	Identity:	85/347 - (24%)
Similarity:	132/347 - (38%)	Gaps:	85/347 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 YQNT--MTSVFQQLREDLS---FVDVTLSCEHGSLKAHKVVLSACSTYF-QKLLLENPCKHPTII 75
            |:|.  :...|.||.....   |.|..|..|..::.||..:|||||.:| ::|..|.|.:...::
Mouse    11 YRNPRFLRVAFLQLHHQQQSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVV 75

  Fly    76 LP-ADIIFTDLKTIIDFVYRGEIDVTESELQGLLRTAEQLKIKGLCETAE--------------- 124
            |. ..:....|:.::||:|..|::|::.|.|.:|..|.||::..| ||.:
Mouse    76 LEMGGLKIQTLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSEL-ETLQLEGGKLVKAPQGRRL 139

  Fly   125 NADDLNDAATATITVSENIQQAVVGNIVNAAIVPGAPSP--------------SLEQQQQHHQQQ 175
            |.:.|...|.|.|:          ..:|.....|..|.|              ||.:::..|::.
Mouse   140 NRECLQPPAAAPIS----------ARVVGPKSRPQTPLPVTQTPSPLGAVRLKSLGEEEGAHKKT 194

  Fly   176 QQQQAQEQHQQQQVHAQQQQQQQQQINAALLTQHGVSSGSVSLSGQLLSSSASGSSGSLAGGQQA 240
            ....|...       :..|.:::.::   .|||...||.|....|...:.|..|.:.
Mouse   195 NLPNADSL-------SDTQLKKKARV---CLTQESRSSPSSQREGPKETKSNPGPTA-------- 241

  Fly   241 SQTPSGLQPT------PRKSRLKRSK-SPDLSSGGGAGSSGGSSSGSTQQQPQPAHHHHPQTIL- 297
              .|| |.|:      |||.||.||| ||.:.:...:....|.||..|    .|......|..:
Mouse   242 --LPS-LYPSVDEQLLPRKIRLSRSKPSPHVYTSTPSSILSGPSSMPT----APGRRLWRQRTVS 299

  Fly   298 -----IQGQNPNSIVSLQQTAD 314
                 :..|.|..:..||.|.|
Mouse   300 KEAQGVDKQKPGEVRPLQSTPD 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
psq	NP_001369078.1	BTB_POZ_BAB-like	34..118	CDD:349624	28/85 (33%)
		HTH_psq	717..>747	CDD:283007
		HTH_psq	767..804	CDD:283007
		HTH_psq	821..866	CDD:283007
		HTH_psq	873..916	CDD:283007
Btbd18	NP_001138572.1	BTB_POZ_BTBD18	20..138	CDD:349602	34/118 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	150..176		6/35 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	188..350		38/159 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	370..394
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	603..637
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	699..723
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910