| Sequence 1: | NP_610592.1 | Gene: | Pef / 36111 | FlyBaseID: | FBgn0033529 | Length: | 199 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000061.1 | Gene: | CAPN3 / 825 | HGNCID: | 1480 | Length: | 821 | Species: | Homo sapiens |
| Alignment Length: | 206 | Identity: | 58/206 - (28%) |
|---|---|---|---|
| Similarity: | 95/206 - (46%) | Gaps: | 18/206 - (8%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 6 GYNPYAQPGGGYAPP------PGAFPPQNAQVSPQAQQW---FSMVDRDRSGKINASELQAAL-- 59
Fly 60 -VNGRGD---H-FSDNACKLMISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEE 119
Fly 120 QELTQAFTQMGFRFSPEFINFLVKKSDPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTIT 184
Fly 185 IGFEDFLTVAI 195 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pef | NP_610592.1 | EFh_PEF_peflin | 34..198 | CDD:320059 | 50/172 (29%) |
| EF-hand motif | 34..63 | CDD:320059 | 11/34 (32%) | ||
| EF-hand motif | 71..100 | CDD:320059 | 11/28 (39%) | ||
| EF-hand motif | 101..131 | CDD:320059 | 11/29 (38%) | ||
| EF-hand motif | 137..166 | CDD:320059 | 5/28 (18%) | ||
| EF-hand motif | 167..198 | CDD:320059 | 6/29 (21%) | ||
| CAPN3 | NP_000061.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 7..37 | ||
| Peptidase_C2 | 75..415 | CDD:459889 | |||
| Domain III | 418..586 | ||||
| Calpain_III | 435..574 | CDD:460050 | |||
| Calpain_u2 | 583..653 | CDD:465216 | 8/36 (22%) | ||
| Linker | 587..649 | 7/32 (22%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 609..652 | 8/35 (23%) | |||
| Domain IV | 650..821 | 50/172 (29%) | |||
| EFh_PEF_CAPN3 | 653..821 | CDD:320065 | 49/169 (29%) | ||
| EF-hand motif | 653..681 | CDD:320065 | 8/28 (29%) | ||
| EF-hand motif | 696..725 | CDD:320065 | 11/28 (39%) | ||
| EF-hand motif | 726..756 | CDD:320065 | 11/29 (38%) | ||
| EF-hand motif | 761..790 | CDD:320065 | 5/29 (17%) | ||
| EF-hand motif | 791..821 | CDD:320065 | 6/29 (21%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||