DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG17765 and CAPN1

DIOPT Version :9

Sequence 1:NP_610592.1 Gene:CG17765 / 36111 FlyBaseID:FBgn0033529 Length:199 Species:Drosophila melanogaster
Sequence 2:NP_001185797.1 Gene:CAPN1 / 823 HGNCID:1476 Length:714 Species:Homo sapiens


Alignment Length:225 Identity:50/225 - (22%)
Similarity:90/225 - (40%) Gaps:44/225 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 PGGGYAPPPGAFPPQ----------------NAQVSPQAQ---------------QWFSMVDRDR 46
            |.|.|...|..|.|.                ..::..|.|               :.|..:.|..
Human   490 PPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQANLPDEQVLSEEEIDENFKALFRQL 554

  Fly    47 SG---KINASELQAALVNGRGDH-------FSDNACKLMISMFDNDASGTIDIYEFEKLYNYINQ 101
            :|   :|:..||:..|......|       ||..:|:.|:::.|.|.:|.:.:.||..|:|.|..
Human   555 AGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRN 619

  Fly   102 WLQVFKTYDQDSSGHIEEQELTQAFTQMGFRFSPEFINFLVKK-SDPQGHKEVSVDQFIVLCVQV 165
            :|.:|:.:|.|.||.:...|:..|....||:.:.:....::.: |:|.  ..|..|.|:...|::
Human   620 YLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPD--LAVDFDNFVCCLVRL 682

  Fly   166 QRFTEAFRQRDTQQNGTITIGFEDFLTVAI 195
            :.....|:..||..:|.:|.....:|.:.:
Human   683 ETMFRFFKTLDTDLDGVVTFDLFKWLQLTM 712

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17765NP_610592.1 FRQ1 26..162 CDD:227455 38/177 (21%)
EFh 39..92 CDD:238008 15/62 (24%)
EFh 105..159 CDD:298682 13/54 (24%)
CAPN1NP_001185797.1 Peptidase_C2 56..352 CDD:306994
Domain III 355..526 6/35 (17%)
Calpain_III 364..524 CDD:238132 6/33 (18%)
Linker 527..542 2/14 (14%)
Domain IV 543..713 42/172 (24%)
EFh_PEF_CAPN1 546..714 CDD:320073 42/169 (25%)
EF-hand motif 546..574 CDD:320073 7/27 (26%)
EF-hand motif 589..618 CDD:320073 9/28 (32%)
EF-hand motif 619..649 CDD:320073 8/29 (28%)
EF-hand motif 655..683 CDD:320073 6/29 (21%)
EF-hand motif 685..714 CDD:320073 6/28 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.