Protein Alignment Pef and SRI

DIOPT Version :10

• Sequence 1: NP_610592.1
• Gene: Pef / 36111
• FlyBaseID: FBgn0033529
• Length: 199
• Species: Drosophila melanogaster
• Sequence 2: NP_003121.1
• Gene: SRI / 6717
• HGNCID: 11292
• Length: 198
• Species: Homo sapiens
• Alignment Length: 203
• Identity: 75/203 - (36%)
• Similarity: 113/203 - (55%)
• Gaps: 23/203 - (11%)

  Fly     1 MSY------GQGYNPYAQPGGGYAPPPG--AFPPQNAQVSPQAQQWFSMVDRDRSGKINASELQA 57
            |:|      |.||.|     |||...||  |||   .|.......:|:.| ..:.|:|:|.|||.
Human     1 MAYPGHPGAGGGYYP-----GGYGGAPGGPAFP---GQTQDPLYGYFAAV-AGQDGQIDADELQR 56

  Fly    58 AL----VNGRGDHFSDNACKLMISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIE 118
            .|    :.|....|:...|:||:||.|.|.|||:...||::|:..:|.|.|.|.::|.|.||.::
Human    57 CLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVD 121

  Fly   119 EQELTQAFTQMGFRFSPEFINFLVKKSDPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTI 183
            .|||.:|.|.||||.||:.:|.:.|:....|  :::.|.:|..||:::..|::||:|||.|.|.:
Human   122 PQELQKALTTMGFRLSPQAVNSIAKRYSTNG--KITFDDYIACCVKLRALTDSFRRRDTAQQGVV 184

  Fly   184 TIGFEDFL 191
            ...::||:
Human   185 NFPYDDFI 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pef	NP_610592.1	EFh_PEF_peflin	34..198	CDD:320059	60/162 (37%)
		EF-hand motif	34..63	CDD:320059	9/32 (28%)
		EF-hand motif	71..100	CDD:320059	13/28 (46%)
		EF-hand motif	101..131	CDD:320059	13/29 (45%)
		EF-hand motif	137..166	CDD:320059	7/28 (25%)
		EF-hand motif	167..198	CDD:320059	10/25 (40%)
SRI	NP_003121.1	EFh_PEF_sorcin	34..198	CDD:320062	60/162 (37%)
		EF-hand motif	34..62	CDD:320062	9/28 (32%)
		EF-hand motif	74..103	CDD:320062	13/28 (46%)
		EF-hand motif	104..134	CDD:320062	13/29 (45%)
		EF-hand motif	140..167	CDD:320062	7/28 (25%)
		EF-hand motif	168..198	CDD:320062	10/25 (40%)