DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17765 and PEF1

DIOPT Version :9

Sequence 1:NP_610592.1 Gene:CG17765 / 36111 FlyBaseID:FBgn0033529 Length:199 Species:Drosophila melanogaster
Sequence 2:NP_036524.1 Gene:PEF1 / 553115 HGNCID:30009 Length:284 Species:Homo sapiens


Alignment Length:202 Identity:87/202 - (43%)
Similarity:115/202 - (56%) Gaps:20/202 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 PY--AQPGGGYAPPP--------------GAFPPQNAQVSPQAQQWFSMVDRDRSGKINASELQA 57
            ||  |.|||.|..||              |..||   .|.|:|..||..||.|.||.|:..||:.
Human    80 PYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPP---NVDPEAYSWFQSVDSDHSGYISMKELKQ 141

  Fly    58 ALVNGRGDHFSDNACKLMISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEEQEL 122
            ||||.....|:|..|.:||:|||...||.||:|.|..|:.:|.||..:|:.||:|.||.|...||
Human   142 ALVNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTEL 206

  Fly   123 TQAFTQMGFRFSPEFINFLVKKSDPQ-GHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTITIG 186
            .||.:|||:..||:|...||.:..|: .:..:.:|:||.:|.|:|..|||||::||...|.|.:.
Human   207 QQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLS 271

  Fly   187 FEDFLTV 193
            ||||:|:
Human   272 FEDFVTM 278

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17765NP_610592.1 FRQ1 26..162 CDD:227455 59/136 (43%)
EFh 39..92 CDD:238008 26/52 (50%)
EFh 105..159 CDD:298682 21/54 (39%)
PEF1NP_036524.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..111 10/30 (33%)
9 X 9 AA approximate tandem repeat of [AP]-P-G-G-P-Y-G-G-P-P. /evidence=ECO:0000305 21..109 9/28 (32%)
EFh_PEF_peflin 118..283 CDD:320059 73/161 (45%)
EF-hand motif 118..147 CDD:320059 15/28 (54%)
EF-hand motif 155..184 CDD:320059 13/28 (46%)
EF-hand motif 185..215 CDD:320059 15/29 (52%)
Required for interaction with PDCD6. /evidence=ECO:0000269|PubMed:11883899 204..284 33/75 (44%)
EF-hand motif 221..251 CDD:320059 9/29 (31%)
EF-hand motif 252..283 CDD:320059 14/27 (52%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 61 1.000 Domainoid score I10510
eggNOG 1 0.900 - - E1_KOG0037
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H56569
Inparanoid 1 1.050 163 1.000 Inparanoid score I4214
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54126
OrthoDB 1 1.010 - - D1330600at2759
OrthoFinder 1 1.000 - - FOG0000697
OrthoInspector 1 1.000 - - oto88700
orthoMCL 1 0.900 - - OOG6_100410
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2225
SonicParanoid 1 1.000 - - X1327
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1413.770

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