DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17765 and capn13

DIOPT Version :9

Sequence 1:	NP_610592.1	Gene:	CG17765 / 36111	FlyBaseID:	FBgn0033529	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001008025.1	Gene:	capn13 / 493387	XenbaseID:	XB-GENE-6045506	Length:	763	Species:	Xenopus tropicalis

Alignment Length:	154	Identity:	38/154 - (24%)
Similarity:	73/154 - (47%)	Gaps:	12/154 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 DRSGKINASELQAAL----------VNGRGDHFSDNACKLMISMFDNDASGTIDIYEFEKLYNYI 99
            ::|.::.|.:||..|          ..|||| |:.:||:.::.:.|.:|:|.:.:.||.:|:..:
Frog   604 NKSSELYAEQLQRLLNEVIIKDQTFAGGRGD-FTLDACRGILMLMDLNANGRLSLQEFGRLWKRL 667

  Fly   100 NQWLQVFKTYDQDSSGHIEEQELTQAFTQMGFRFSPEFINFLVKKSDPQGHKEVSVDQFIVLCVQ 164
            |....:|::.|.:.:|.|:...|.:|....|...|...||.:|.:......| :|...|:...::
Frog   668 NMCKDMFRSIDGNQTGFIDASGLKKAVQLAGLPISNALINVMVLRYANSSEK-LSFADFVCCMIR 731

  Fly   165 VQRFTEAFRQRDTQQNGTITIGFE 188
            ::..|:.|:.......|....|.|
Frog   732 LETVTKVFKNLSKDGRGVYLSGEE 755

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17765	NP_610592.1	FRQ1	26..162	CDD:227455	33/126 (26%)
		EFh	39..92	CDD:238008	15/56 (27%)
		EFh	105..159	CDD:298682	13/53 (25%)
capn13	NP_001008025.1	Peptidase_C2	48..341	CDD:366222
		Calpain_III	364..497	CDD:366446
		EFh_PEF_CAPN13_14	595..763	CDD:320070	38/154 (25%)
		EF-hand motif	595..622	CDD:320070	5/17 (29%)
		EF-hand motif	639..668	CDD:320070	8/28 (29%)
		EF-hand motif	669..699	CDD:320070	6/29 (21%)
		EF-hand motif	705..733	CDD:320070	6/28 (21%)
		EF-hand motif	735..763	CDD:320070	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910