DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17765 and Capn13

DIOPT Version :9

Sequence 1:	NP_610592.1	Gene:	CG17765 / 36111	FlyBaseID:	FBgn0033529	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001028616.1	Gene:	Capn13 / 381122	MGIID:	2685789	Length:	665	Species:	Mus musculus

Alignment Length:	166	Identity:	36/166 - (21%)
Similarity:	73/166 - (43%)	Gaps:	18/166 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PQNAQVSPQAQQWFSMVDRDRSGKINASELQAA-----LVNGRGDHFSDNACKLMISMFDNDASG 85
            |:|.     ::...|....|:...|:|::||:.     |....||.||.:.|:.::::.|...:|
Mouse   493 PENG-----SRNSISYTYMDQGLDIDATQLQSLLNQEFLTGPPGDTFSLDQCQSIMALMDLKVNG 552

  Fly    86 TIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEEQELTQAFTQ----MGFRFSPEFINFL-VKKS 145
            .:|..||.:|.:.:.....:|::. |...|.:...:|.:....    :|...|.|.::.: ::.|
Mouse   553 RLDQEEFARLRSRLIHCQHIFQSI-QRRPGVLLSSDLWKVIENTDFLVGIFISSELLSLMALRYS 616

  Fly   146 DPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNG 181
            |..|  .||....:...::::...:|||.......|
Mouse   617 DSSG--RVSFPTLVCFLIRLETMAKAFRNLSKDGKG 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17765	NP_610592.1	FRQ1	26..162	CDD:227455	32/145 (22%)
		EFh	39..92	CDD:238008	15/57 (26%)
		EFh	105..159	CDD:298682	12/58 (21%)
Capn13	NP_001028616.1	Peptidase_C2	31..327	CDD:279042
Capn13	NP_001028616.1	Calpain_III	343..469	CDD:294111
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836666
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0037
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740