DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17765 and capn8

DIOPT Version :9

Sequence 1:	NP_610592.1	Gene:	CG17765 / 36111	FlyBaseID:	FBgn0033529	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001231009.1	Gene:	capn8 / 337730	ZFINID:	ZDB-GENE-050522-279	Length:	701	Species:	Danio rerio

Alignment Length:	225	Identity:	51/225 - (22%)
Similarity:	92/225 - (40%)	Gaps:	44/225 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PGGGYAPPPGAFPP----------------------------------QNAQVSPQAQQWFSMVD 43
            |.|.|...|..|.|                                  ....:.|..::.||.|.
Zfish   478 PPGEYIIIPSTFEPHRKGSFILRVFAEKEADASQIGTEISADVKKHFISEKDIDPHFKRLFSQVA 542

  Fly    44 RDRSGKINASELQAAL--------VNGRGDHFSDNACKLMISMFDNDASGTIDIYEFEKLYNYIN 100
            ...| :::..|||..|        .|.:.|.||...|:.:||:.|.|.||.:.:.||..|:..|.
Zfish   543 GSDS-EVSVLELQQILNTVVSKRKSNVKTDGFSLETCRHIISLLDKDGSGKLGLLEFHTLWMKIQ 606

  Fly   101 QWLQVFKTYDQDSSGHIEEQELTQAFTQMGFRFSPEFINFLVKKSDPQGHKEVSVDQFIVLCVQV 165
            ::|::||..|.|:||.:...|:..|..:.||:.:.:.:..|:.:...|.: .:..|.|:...:::
Zfish   607 KYLEIFKHRDTDNSGTMSSLEMRDAVKEAGFQLNNDVLEVLIARYANQEY-AIDFDSFVSCLIRL 670

  Fly   166 QRFTEAFRQRDTQQNGTITIGFEDFLTVAI 195
            :...:.|:..|.:..|.|.:....:|.:|:
Zfish   671 ELLFKMFQLFDKKNTGKIELDILQWLCLAL 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17765	NP_610592.1	FRQ1	26..162	CDD:227455	40/177 (23%)
		EFh	39..92	CDD:238008	19/60 (32%)
		EFh	105..159	CDD:298682	13/53 (25%)
capn8	NP_001231009.1	Peptidase_C2	46..342	CDD:279042
		Calpain_III	356..507	CDD:279416	6/28 (21%)
		EFh	578..633	CDD:238008	20/54 (37%)
		EFh	607..691	CDD:298682	19/84 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910