DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17765 and Capn12

DIOPT Version :9

Sequence 1:	NP_610592.1	Gene:	CG17765 / 36111	FlyBaseID:	FBgn0033529	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	XP_038967508.1	Gene:	Capn12 / 308476	RGDID:	1307341	Length:	766	Species:	Rattus norvegicus

Alignment Length:	151	Identity:	36/151 - (23%)
Similarity:	64/151 - (42%)	Gaps:	19/151 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 AQQWFSMVDRDRSGKINASELQA----ALVNGRGD-----HFSDNACKLMISMFDNDASGTIDIY 90
            ||.:..:...:.  ::||.:||.    ||...|.:     ......|:.::..|..  ...:.:|
  Rat   553 AQLFLELAGEEE--ELNALQLQTLISIALEPARNNTRTSGEIGLRTCEQLVQCFGR--GQRLALY 613

  Fly    91 EFEKLYNYINQWLQVFKTYDQDSSGHIEEQELTQAFTQMGFRFSPEFINFLVKKSDPQGHKEVSV 155
            .|::|:.::..|...|..:|:|:||.:...||..|.|..||..:.:....|..:   ..:..:.|
  Rat   614 HFQELWGHLLSWQATFDKFDEDASGTMNSCELRLALTAAGFHLNNQLTQALTSR---YRNSRLRV 675

  Fly   156 D-QFIVLCVQVQRFTEAFRQR 175
            | :..|.|  ..|.|..||:|
  Rat   676 DFEHFVCC--AARLTCIFRER 694

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17765	NP_610592.1	FRQ1	26..162	CDD:227455	30/136 (22%)
		EFh	39..92	CDD:238008	10/61 (16%)
		EFh	105..159	CDD:298682	14/54 (26%)
Capn12	XP_038967508.1	Peptidase_C2	46..339	CDD:395523
		Calpain_III	352..530	CDD:238132
		EFh_PEF	567..693	CDD:355382	32/132 (24%)
		EF-hand motif	596..623	CDD:320054	5/28 (18%)
		EF-hand motif	624..654	CDD:320054	10/29 (34%)
		EF-hand motif	660..688	CDD:320054	6/32 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340363
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840