DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17765 and Pef1

DIOPT Version :9

Sequence 1:	NP_610592.1	Gene:	CG17765 / 36111	FlyBaseID:	FBgn0033529	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001007652.1	Gene:	Pef1 / 297900	RGDID:	1359536	Length:	283	Species:	Rattus norvegicus

Alignment Length:	194	Identity:	83/194 - (42%)
Similarity:	112/194 - (57%)	Gaps:	8/194 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YGQGY-NPY-AQPGGGYAPPPGAFPPQNAQVSPQAQQWFSMVDRDRSGKINASELQAALVNGRGD 65
            |||.: :|| .||.|.|.  .|..||   .|.|:|..||..||.|.||.|:..||:.||||....
  Rat    89 YGQAHPSPYGTQPPGPYG--QGGVPP---NVDPEAYSWFQSVDADHSGYISLKELKQALVNSNWS 148

  Fly    66 HFSDNACKLMISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEEQELTQAFTQMG 130
            .|:|..|.:||:|||...:|.||:..|..|:.::.||..:|:.||:|.||.|...||.||.:|||
  Rat   149 SFNDETCLMMINMFDKTKTGRIDVVGFSALWKFLQQWKNLFQQYDRDHSGSISSTELQQALSQMG 213

  Fly   131 FRFSPEFINFLVKK-SDPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTITIGFEDFLTV 193
            :..||:|...||.: ........:.:|.||.:|.|:|..|||||::||...|.|.:.||||:|:
  Rat   214 YNLSPQFTQLLVSRYCTRSAIPAMQLDCFIKVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTM 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17765	NP_610592.1	FRQ1	26..162	CDD:227455	55/136 (40%)
		EFh	39..92	CDD:238008	24/52 (46%)
		EFh	105..159	CDD:298682	20/54 (37%)
Pef1	NP_001007652.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44
		9 X 9 AA approximate tandem repeat of [AP]-P-G-G-P-Y-G-G-P-P	21..108		9/20 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	56..114		12/29 (41%)
		EF-hand_7	122..178	CDD:290234	25/55 (45%)
		EFh	122..171	CDD:238008	22/48 (46%)
		EF-hand_6	184..213	CDD:290141	14/28 (50%)
		EF-hand_7	186..277	CDD:290234	38/90 (42%)
		EFh	186..277	CDD:298682	38/90 (42%)
		Required for interaction with PDCD6. /evidence=ECO:0000250\|UniProtKB:Q9UBV8	203..283		32/75 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	55	1.000	Domainoid score	I10901
eggNOG	1	0.900	-	-		E1_KOG0037
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56569
Inparanoid	1	1.050	155	1.000	Inparanoid score	I4226
OMA	1	1.010	-	-		QHG54126
OrthoDB	1	1.010	-	-		D1330600at2759
OrthoFinder	1	1.000	-	-		FOG0000697
OrthoInspector	1	1.000	-	-		oto95831
orthoMCL	1	0.900	-	-		OOG6_100410
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1327
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.740