Protein Alignment Pef and GCA

DIOPT Version :10

• Sequence 1: NP_610592.1
• Gene: Pef / 36111
• FlyBaseID: FBgn0033529
• Length: 199
• Species: Drosophila melanogaster
• Sequence 2: XP_006712461.1
• Gene: GCA / 25801
• HGNCID: 15990
• Length: 259
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 64/198 - (32%)
• Similarity: 101/198 - (51%)
• Gaps: 17/198 - (8%)

  Fly     1 MSYGQGYNPYAQPG-----GGYAPPPGAFPPQNAQVSPQAQQWFSMVDRDRSGKINASELQAAL- 59
            |..||   |..:.|     .||:.|  |:....:........:||.| ..:.|:::|.|||..|
Human    46 MQMGQ---PVPETGPAILLDGYSGP--AYSDTYSSAGDSVYTYFSAV-AGQDGEVDAEELQRCLT 104

  Fly    60 ---VNGRGDHFSDNACKLMISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEEQE 121
               :||....||...|::||:|.|.|.:|.:....|::|:..:|.|.:.|.|.|||.||.:|..|
Human   105 QSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHE 169

  Fly   122 LTQAFTQMGFRFSPEFINFLVKKSDPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTITIG 186
            |.||...||:|.||:.:..:||:....|  .:..|.::..||:::..|:.||:||..|.|:....
Human   170 LRQAIGLMGYRLSPQTLTTIVKRYSKNG--RIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFI 232

  Fly   187 FED 189
            ::|
Human   233 YDD 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pef	NP_610592.1	EFh_PEF_peflin	34..198	CDD:320059	55/160 (34%)
		EF-hand motif	34..63	CDD:320059	10/32 (31%)
		EF-hand motif	71..100	CDD:320059	9/28 (32%)
		EF-hand motif	101..131	CDD:320059	14/29 (48%)
		EF-hand motif	137..166	CDD:320059	6/28 (21%)
		EF-hand motif	167..198	CDD:320059	8/23 (35%)
GCA	XP_006712461.1	EFh_PEF	79..235	CDD:355382	54/158 (34%)
		EF-hand motif	79..107	CDD:320054	9/28 (32%)
		EF-hand motif	119..148	CDD:320054	9/28 (32%)
		EF-hand motif	149..178	CDD:320054	13/28 (46%)
		EF-hand motif	185..212	CDD:320054	6/28 (21%)