DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17765 and Pdcd6

DIOPT Version :9

Sequence 1:	NP_610592.1	Gene:	CG17765 / 36111	FlyBaseID:	FBgn0033529	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_035181.1	Gene:	Pdcd6 / 18570	MGIID:	109283	Length:	191	Species:	Mus musculus

Alignment Length:	189	Identity:	76/189 - (40%)
Similarity:	112/189 - (59%)	Gaps:	10/189 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YNPYAQPGGGYAPPPGAFPPQNAQVSPQAQQW--FSMVDRDRSGKINASELQAALVNGRGDHFSD 69
            |.|  .||||..|..||..|.      |:..|  |..||:||||.|:.:|||.||.||....|:.
Mouse     6 YRP--GPGGGPGPAAGAALPD------QSFLWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNP 62

  Fly    70 NACKLMISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEEQELTQAFTQMGFRFS 134
            ...:.:|||||.:....::..||..::.||..|..||:|||:|:||.|::.||.||.:..|:|.|
Mouse    63 VTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLS 127

  Fly   135 PEFINFLVKKSDPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTITIGFEDFLTV 193
            .:|.:.|::|.|.||..:::.|.||..|:.:||.|:.||:.||.|:|.|.:.:|.:|::
Mouse   128 DQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSM 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17765	NP_610592.1	FRQ1	26..162	CDD:227455	54/137 (39%)
		EFh	39..92	CDD:238008	21/52 (40%)
		EFh	105..159	CDD:298682	23/53 (43%)
Pdcd6	NP_035181.1	EFh_PEF_ALG-2	27..191	CDD:320058	65/160 (41%)
		EF-hand motif	27..56	CDD:320058	15/28 (54%)
		EF-hand motif	64..93	CDD:320058	8/28 (29%)
		EF-hand motif	94..123	CDD:320058	14/28 (50%)
		EF-hand motif	130..159	CDD:320058	10/28 (36%)
		EF-hand motif	161..189	CDD:320058	10/26 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0037
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54126
OrthoDB	1	1.010	-	-		D1330600at2759
OrthoFinder	1	1.000	-	-		FOG0000697
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100410
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1327
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730