DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17765 and Sri

DIOPT Version :9

Sequence 1:	NP_610592.1	Gene:	CG17765 / 36111	FlyBaseID:	FBgn0033529	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001074443.1	Gene:	Sri / 109552	MGIID:	98419	Length:	198	Species:	Mus musculus

Alignment Length:	203	Identity:	74/203 - (36%)
Similarity:	113/203 - (55%)	Gaps:	23/203 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSY------GQGYNPYAQPGGGYAPPPG--AFPPQNAQVSPQAQQWFSMVDRDRSGKINASELQA 57
            |:|      |.||.|     |||...||  |||   .|.......:|:.| ..:.|:|:|.|||.
Mouse     1 MAYPGHPGAGGGYYP-----GGYGGAPGGPAFP---GQTQDPLYGYFAAV-AGQDGQIDADELQR 56

  Fly    58 AL----VNGRGDHFSDNACKLMISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIE 118
            .|    :.|....|:...|:||:||.|.|.|||:...||::|:..:|.|.|.|.::|.|.||.::
Mouse    57 CLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDSDRSGTVD 121

  Fly   119 EQELTQAFTQMGFRFSPEFINFLVKKSDPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTI 183
            .|||.:|.|.||||.||:.:|.:.|:....|  :::.|.:|..||:::..|::||:||:.|.|.:
Mouse   122 PQELQKALTTMGFRLSPQTVNSVAKRYSTSG--KITFDDYIACCVKLRALTDSFRRRDSGQQGVV 184

  Fly   184 TIGFEDFL 191
            ...::||:
Mouse   185 NFSYDDFI 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17765	NP_610592.1	FRQ1	26..162	CDD:227455	49/139 (35%)
		EFh	39..92	CDD:238008	21/56 (38%)
		EFh	105..159	CDD:298682	20/53 (38%)
Sri	NP_001074443.1	EFh_PEF_sorcin	34..198	CDD:320062	59/162 (36%)
		EF-hand motif	34..62	CDD:320062	9/28 (32%)
		EF-hand motif	74..103	CDD:320062	13/28 (46%)
		EF-hand motif	104..134	CDD:320062	13/29 (45%)
		EF-hand motif	140..167	CDD:320062	7/28 (25%)
		EF-hand motif	168..198	CDD:320062	9/25 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0037
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54126
OrthoDB	1	1.010	-	-		D1330600at2759
OrthoFinder	1	1.000	-	-		FOG0000697
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100410
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.730