Protein Alignment Pef and PDCD6

DIOPT Version :10

• Sequence 1: NP_610592.1
• Gene: Pef / 36111
• FlyBaseID: FBgn0033529
• Length: 199
• Species: Drosophila melanogaster
• Sequence 2: NP_037364.1
• Gene: PDCD6 / 10016
• HGNCID: 8765
• Length: 191
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 73/184 - (39%)
• Similarity: 111/184 - (60%)
• Gaps: 6/184 - (3%)

  Fly    12 QPGGGYAPPPGAFPPQNAQVSPQAQQW--FSMVDRDRSGKINASELQAALVNGRGDHFSDNACKL 74
            :||.|..|.|.|    .|.:..|:..|  |..||:||||.|:.:|||.||.||....|:....:.
Human     7 RPGPGAGPGPAA----GAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRS 67

  Fly    75 MISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEEQELTQAFTQMGFRFSPEFIN 139
            :|||||.:....::..||..::.||..|..||:|||:|:||.|::.||.||.:..|:|.|.:|.:
Human    68 IISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHD 132

  Fly   140 FLVKKSDPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTITIGFEDFLTV 193
            .|::|.|.||..:::.|.||..|:.:||.|:.||:.||.|:|.|.:.:|.:|::
Human   133 ILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSM 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pef	NP_610592.1	EFh_PEF_peflin	34..198	CDD:320059	66/162 (41%)
		EF-hand motif	34..63	CDD:320059	16/30 (53%)
		EF-hand motif	71..100	CDD:320059	8/28 (29%)
		EF-hand motif	101..131	CDD:320059	14/29 (48%)
		EF-hand motif	137..166	CDD:320059	10/28 (36%)
		EF-hand motif	167..198	CDD:320059	11/27 (41%)
PDCD6	NP_037364.1	EFh_PEF_ALG-2	27..191	CDD:320058	65/160 (41%)
		EF-hand motif	27..56	CDD:320058	15/28 (54%)
		EF-hand motif	64..93	CDD:320058	8/28 (29%)
		EF-hand motif	94..124	CDD:320058	14/29 (48%)
		EF-hand motif	130..159	CDD:320058	10/28 (36%)
		EF-hand motif	160..191	CDD:320058	11/27 (41%)