DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trsn and TSN

DIOPT Version :9

Sequence 1:	NP_610591.1	Gene:	trsn / 36110	FlyBaseID:	FBgn0033528	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_004613.1	Gene:	TSN / 7247	HGNCID:	12379	Length:	228	Species:	Homo sapiens

Alignment Length:	216	Identity:	114/216 - (52%)
Similarity:	148/216 - (68%)	Gaps:	2/216 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DIFSNYQKYIDNEQEVRENIRIVVREIEHLSKEAQIKLQIIH--SDLSQISAACGLARKQVELCA 70
            :||...|.::..||::||.||.||:.:|..::|....||.:|  :....|...|..||:......
Human     5 EIFVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQGVHQGAGFQDIPKRCLKAREHFGTVK 69

  Fly    71 QKYQKLAELVPAGQYYRYSDHWTFITQRLIFIIALVIYLEAGFLVTRETVAEMLGLKISQSEGFH 135
            .....|....||.||||:.:||.|:.|||:|:.|.|:|||...|||||.|.|:||::..:.:|||
Human    70 THLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAVTEILGIEPDREKGFH 134

  Fly   136 LDVEDYLLGILQLASELSRFATNSVTMGDYERPLNISHFIGDLNTGFRLLNLKNDGLRKRFDALK 200
            |||||||.|:|.|||||||.:.||||.|||.|||:||.||.:|::||||||||||.||||:|.||
Human   135 LDVEDYLSGVLILASELSRLSVNSVTAGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDGLK 199

  Fly   201 YDVKKIEEVVYDVSIRGLSSK 221
            |||||:||||||:||||.:.:
Human   200 YDVKKVEEVVYDLSIRGFNKE 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trsn	NP_610591.1	Translin	13..217	CDD:271349	110/205 (54%)
TSN	NP_004613.1	Translin	10..216	CDD:271349	110/205 (54%)
		DNA/RNA binding	86..90		1/3 (33%)
		Leucine-zipper. /evidence=ECO:0000255	177..198		16/20 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141392
Domainoid	1	1.000	213	1.000	Domainoid score	I2769
eggNOG	1	0.900	-	-		E1_KOG3067
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3397
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3539
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55801
OrthoDB	1	1.010	-	-		D1187354at2759
OrthoFinder	1	1.000	-	-		FOG0006024
OrthoInspector	1	1.000	-	-		oto90305
orthoMCL	1	0.900	-	-		OOG6_104779
Panther	1	1.100	-	-	LDO	PTHR10741
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1560
SonicParanoid	1	1.000	-	-		X4320
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800