Protein Alignment whd and YAT1

DIOPT Version :9

• Sequence 1: NP_001163111.1
• Gene: whd / 36109
• FlyBaseID: FBgn0261862
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_009420.1
• Gene: YAT1 / 851285
• SGDID: S000000080
• Length: 687
• Species: Saccharomyces cerevisiae
• Alignment Length: 708
• Identity: 184/708 - (25%)
• Similarity: 292/708 - (41%)
• Gaps: 139/708 - (19%)

  Fly   170 SLPRLPLPSVKDTMTRYLRSVRPLLDDENYTRMERLAKEFE-----QTIGKKLQWY--LILKSWW 227
            :|.|||:|.::||:.|||..|.||.|:....|..|.....|     .|:.::|..|  .:.:|..
Yeast     3 NLKRLPIPPLQDTLNRYLARVEPLQDERQNRRTRRTVLSAENLDALNTLHERLLEYDARLAESNP 67

  Fly   228 STNYVSD-WWEEYVYLRGRSPLCVNSNF-------------------YGTDAIFMNLTDKQAARA 272
            .::|:.. |::.|:.......|.||..|                   ||...:       |..||
Yeast    68 ESSYIEQFWYDAYLLYDATVVLNVNPYFQLQDDPTIKDTPETAAQGPYGAHTV-------QVRRA 125

  Fly   273 ANVISLLLNFRRLIEHQELQPIMVQGMIPLCSWQYERTFNTARVP--------GLETDRIIHYRD 329
            |.:.:.:|.|.|.|.|..|:...|:|..||...||||.|.::|:|        .|:||...|
Yeast   126 ARLTTSILKFIRQIRHGTLRTDTVRGKTPLSMDQYERLFGSSRIPPGPGEPSCHLQTDATSH--- 187

  Fly   330 SNHIVVLHKGCYYKMLIY---YKGRILRPCELQVQIEEILKGKATPVEGEEHLAALTAWNRSKWA 391
              |:|.:::|.:|...:.   .:.....|.:|:..:..|:....:...|.......|..:|..|:
Yeast   188 --HVVAMYRGQFYWFDVLDTRNEPIFATPEQLEWNLYSIIMDAESAGSGSAPFGVFTTESRRVWS 250

  Fly   392 EARNTFFSWG--VNQTSLRTIESAAFVLSLDDEPFEFDLARPELLDNFGKKLLHGNG-------- 446
            ..|:..|...  .|..:|:.|:||.||:.|||..|..|..     |...:.:|.|..
Yeast   251 NIRDYLFHADDCTNWRNLKLIDSALFVVCLDDVAFAADQQ-----DELTRSMLCGTSTINLDPHQ 310

  Fly   447 ------------YNRWFDKCFTVCVGTNGRVGFNAEHTWSDAAIASHMWENLIVDDLVSDGYDET 499
                        .|||:|| ..:.|..||:.|.|.|||..|......:..::..|.::|.....|
Yeast   311 HQPPLNVQTGTCLNRWYDK-LQLIVTKNGKAGINFEHTGVDGHTVLRLATDIYTDSILSFARGVT 374

  Fly   500 GNT-------KGTPAFQP-----------PTPTRLTWDLKPCL-AQIEEATIDVTKLINEVNLRI 545
            .|.       .|.|:...           ..|.:|.|.....| :.:..|...::.||::.....
Yeast   375 KNVVDIFSDDDGKPSSSSLASAAHSANLITIPRKLEWRTDNFLQSSLHFAETRISDLISQYEFVN 439

  Fly   546 LVHQDYGKGFMK---KCRISPDAYIQMALQLAYYRDAGRFSLTYEASMTRLFREGRTETVRPCTI 607
            |...:||...:|   ||  ||||::|...|:||:...|||...||.:||:.|:.||||.:|..|.
Yeast   440 LDFSNYGASHIKTVFKC--SPDAFVQQVFQVAYFALYGRFETVYEPAMTKAFQNGRTEAIRSVTG 502

  Fly   608 ESSAWVKAMQNPNTTNDERVKMMQAACDRHQLGYQDAMCGRGIDRHLFCLYVVSKYLEVDSPFLN 672
            :|..:||::.:.:.::..:::::..||..|....::...|.|.||||:.||.:......|...|.
Yeast   503 QSKLFVKSLLDQDASDATKIQLLHDACTAHSQITRECSQGLGQDRHLYALYCLWNQWYKDKLELP 567

  Fly   673 EVL-SEPWR------LSTSQTPHGQTPKMDLKKHPNCISAGG------GFGPVADDGYGVSYIIA 724
            .:. .:.|.      ||||                ||   |.      |||||..:|:|:.|||.
Yeast   568 PIFRDKSWTTMQNNVLSTS----------------NC---GNPCLKSFGFGPVTANGFGIGYIIR 613

  Fly   725 GENLIFFHISAKTTCQQTDVHRFAQNISQALSDIRSMFEQHMKDHPKPAKSLTNGKST 782
            ..:     :|...:.:.....|||..:.::|.:|..:|::......|||...|...:|
Yeast   614 DHS-----VSVVVSSRHRQTARFASLMEKSLLEIDRIFKRQQARAAKPAARTTASANT 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
whd	NP_001163111.1	CPT_N	1..45	CDD:293093
		Carn_acyltransf	171..759	CDD:279140	177/682 (26%)
YAT1	NP_009420.1	Carn_acyltransf	4..642	CDD:395612	177/681 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870