Protein Alignment whd and ChAT

DIOPT Version :10

• Sequence 1: NP_001163111.1
• Gene: whd / 36109
• FlyBaseID: FBgn0261862
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_477004.5
• Gene: ChAT / 42249
• FlyBaseID: FBgn0000303
• Length: 721
• Species: Drosophila melanogaster
• Alignment Length: 703
• Identity: 200/703 - (28%)
• Similarity: 313/703 - (44%)
• Gaps: 111/703 - (15%)

  Fly   130 GWMYESRAPGSRVSLPTMLWVAVVRVLSSWNKPGLYSFQGSLPRLPLPSVKDTMTRYLRSVRPLL 194
            ||      ..|.:|:|.. |::....:..      :.|..:||::|:|::.:||..|:|::.|:.
  Fly    60 GW------KDSILSIPKK-WLSTAESVDE------FGFPDTLPKVPVPALDETMADYIRALEPIT 111

  Fly   195 DDENYTRMERLAKEFE--QTIGKKLQWYLILKSWWSTNYVSDWWEEYVYLRGRSPLCVNSNFYGT 257
            ......|.:.|.::|.  |.||.:|..||:.|.....|:...:|...:|:..|.||.:|||   .
  Fly   112 TPAQLERTKELIRQFSAPQGIGARLHQYLLDKREAEDNWAYYYWLNEMYMDIRIPLPINSN---P 173

  Fly   258 DAIF----MNLTDKQAARAANVISLLLNFRRLIEHQEL---QPIMVQGMIPLCSWQYERTFNTAR 315
            ..:|    .......|..||.::..:|:.|.:::..||   :....:...|||..||.|...:.|
  Fly   174 GMVFPPRRFKTVHDVAHFAARLLDGILSHREMLDSGELPLERAASREKNQPLCMAQYYRLLGSCR 238

  Fly   316 VPGLETD-RIIHYR-----DSNHIVVLHKGCYYKMLIYYKGR-ILRPCELQVQIEEILK------ 367
            .||::.| :.:..|     :..|:||:.:...|.:::....| .|...|:..||..:|.
  Fly   239 RPGVKQDSQFLPSRERLNDEDRHVVVICRNQMYCVVLQASDRGKLSESEIASQILYVLSDAPCLP 303

  Fly   368 GKATPVEGEEHLAALTAWNRSKWAEARNTFFSWGVNQTSLRTIESAAFVLSLDDEPFE------- 425
            .|..||      ..|||..||.||..|........||.:|..||:|..||.| |||..
  Fly   304 AKPVPV------GLLTAEPRSTWARDREMLQEDERNQRNLELIETAQVVLCL-DEPLAGNFNARG 361

  Fly   426 FDLARPEL-------LDNFGKKLLHGNGY-----NRWFDKCFTVCVGTNGRVGFNAEHTWSDAAI 478
            |..|.|.:       ..|...:::||.|.     ||||||...:.:.|:|..|...||:.|:...
  Fly   362 FTGATPTVHRAGDRDETNMAHEMIHGGGSEYNSGNRWFDKTMQLIICTDGTWGLCYEHSCSEGIA 426

  Fly   479 ASHMWENLIVDDLVSDGYDETGNTKGTPAFQPPTPTRLTWDLKPCL-AQIEEATIDVTKLINEVN 542
            ...:.|.:.  ..:.:..||   ..|.|....|.|.||.|.:.|.| .:..:|:..|.|.|::::
  Fly   427 VVQLLEKIY--KKIEEHPDE---DNGLPQHHLPPPERLEWHVGPQLQLRFAQASKSVDKCIDDLD 486

  Fly   543 LRILVHQDYGKGFMKKCRISPDAYIQMALQLAYYRDAGRFSLTYEASMTRLFREGRTETVRPCTI 607
            ..:..:|.|||.|:|.|::|||.|||:|||||:|:..||...|||::.||.|..||.:.:|..:.
  Fly   487 FYVYRYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRLVATYESASTRRFLHGRVDCIRAAST 551

  Fly   608 ESSAWVKAMQNPNTTN--------DE----RVK-----------MMQAACDRHQLGYQDAMCGRG 649
            |:..|.|||......|        ||    :||           :.:.|..|........:.|.|
  Fly   552 EALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKDHLRELFRCAVARQTEVMVKNILGNG 616

  Fly   650 IDRHLFCLYVVSKYL--EVDSPFLNE--VLSEPWRLSTSQTPHGQTPKMDLKKHPNCISAGGGFG 710
            ||..|..|...|..:  |:...|.:|  ::|:.:.|||||........|             |:|
  Fly   617 IDIPLLGLREASIEVTGEMHELFKDESYIISQCFLLSTSQVACSTDSFM-------------GYG 668

  Fly   711 PVADDGYGVSYIIAGENLIFFHISAKTTCQQTDVHRFAQNISQALSDIRSMFE 763
            ||...|||.||....|.::|. :||..:|:.|...|:|:::..:|..:|.:.:
  Fly   669 PVTPRGYGCSYNPHPEQIVFC-VSAFYSCEDTSASRYAKSLQDSLDIMRDLLQ 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
whd	NP_001163111.1	CPT_N	1..47	CDD:465132
		Carn_acyltransf	174..753	CDD:459926	189/647 (29%)
ChAT	NP_477004.5	Carn_acyltransf	92..710	CDD:459926	189/646 (29%)