Protein Alignment whd and Cpt1a

DIOPT Version :10

• Sequence 1: NP_001163111.1
• Gene: whd / 36109
• FlyBaseID: FBgn0261862
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_113747.2
• Gene: Cpt1a / 25757
• RGDID: 2396
• Length: 773
• Species: Rattus norvegicus
• Alignment Length: 777
• Identity: 399/777 - (51%)
• Similarity: 533/777 - (68%)
• Gaps: 27/777 - (3%)

  Fly     1 MAEAHAAVAFSFAITHEGFDINYDHEVLNLVWNSGVRSWKKRLARARNGVRNGVYPAHIQSLWLI 65
            |||||.||||.|.:|.:|.|:...||.|..:..||:.||||:..|.:||:..||:||: .|.|||
  Rat     1 MAEAHQAVAFQFTVTPDGIDLRLSHEALKQICLSGLHSWKKKFIRFKNGIITGVFPAN-PSSWLI 64

  Fly    66 SAI------------ALGLHFAGYQAPFNLTNRILVHLPSNTINWQVTACFLAALVVWLSICFTM 118
            ..:            :||: .|......:.|.|    :.|.|.|  :.:..|....:|:::..||
  Rat    65 VVVGVISSMHAKVDPSLGM-IAKISRTLDTTGR----MSSQTKN--IVSGVLFGTGLWVAVIMTM 122

  Fly   119 RYTLKLLLMYKGWMYESRAPGSRVSLPTMLWVAVVRVLSSWNKPGLYSFQGSLPRLPLPSVKDTM 183
            ||:||:||.|.|||:   |...::|..|.:|:|:|:|||. .||.|||||.||||||:|:||||:
  Rat   123 RYSLKVLLSYHGWMF---AEHGKMSRSTKIWMAMVKVLSG-RKPMLYSFQTSLPRLPVPAVKDTV 183

  Fly   184 TRYLRSVRPLLDDENYTRMERLAKEFEQTIGKKLQWYLILKSWWSTNYVSDWWEEYVYLRGRSPL 248
            :|||.|||||:.:|::.||..||::|...:|.||||||.|||||:|||||||||||:|||||.||
  Rat   184 SRYLESVRPLMKEEDFQRMTALAQDFAVNLGPKLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPL 248

  Fly   249 CVNSNFYGTDAIFMNLTDKQAARAANVISLLLNFRRLIEHQELQPIMVQG-MIPLCSWQYERTFN 312
            .||||:|..:.:::..|..|||||.|.|..:|.:||.::.:||:||.:.| .|||||.|:||.||
  Rat   249 MVNSNYYAMEMLYITPTHIQAARAGNTIHAILLYRRTLDREELKPIRLLGSTIPLCSAQWERLFN 313

  Fly   313 TARVPGLETDRIIHYRDSNHIVVLHKGCYYKMLIYYKGRILRPCELQVQIEEILKGKATPVEGEE 377
            |:|:||.|||.|.|.:||.||||.|:|.|:|:.:|:.||:|||.||:.|:::||...:.|..||.
  Rat   314 TSRIPGEETDTIQHIKDSRHIVVYHRGRYFKVWLYHDGRLLRPRELEQQMQQILDDPSEPQPGEA 378

  Fly   378 HLAALTAWNRSKWAEARNTFFSWGVNQTSLRTIESAAFVLSLDDEPFEFDLARPEL-LDNFGKKL 441
            .||||||.:|..||:.|.|:|:.|.|:.||..:|.|||.::||:....:....||. :|::.|.|
  Rat   379 KLAALTAADRVPWAKCRQTYFARGKNKQSLDAVEKAAFFVTLDESEQGYREEDPEASIDSYAKSL 443

  Fly   442 LHGNGYNRWFDKCFTVCVGTNGRVGFNAEHTWSDAAIASHMWENLIVDDLVSDGYDETGNTKGTP 506
            |||..::|||||..|..|..|.::|.||||:|:||.:..|:||.::..|:...||.|.|:.||..
  Rat   444 LHGRCFDRWFDKSITFVVFKNSKIGINAEHSWADAPVVGHLWEYVMATDVFQLGYSEDGHCKGDT 508

  Fly   507 AFQPPTPTRLTWDLK-PCLAQIEEATIDVTKLINEVNLRILVHQDYGKGFMKKCRISPDAYIQMA 570
            ....|.||||.||:. .|...|:.:....:.|.|:|:|.......:|||.:||||.||||:||:|
  Rat   509 NPNIPKPTRLQWDIPGECQEVIDASLSSASLLANDVDLHSFPFDSFGKGLIKKCRTSPDAFIQLA 573

  Fly   571 LQLAYYRDAGRFSLTYEASMTRLFREGRTETVRPCTIESSAWVKAMQNPNTTNDERVKMMQAACD 635
            ||||:|:|.|:|.||||||||||||||||||||.||:||..:|:||.:|.:|.::|:|:.:.||:
  Rat   574 LQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTMESCNFVQAMMDPKSTAEQRLKLFKIACE 638

  Fly   636 RHQLGYQDAMCGRGIDRHLFCLYVVSKYLEVDSPFLNEVLSEPWRLSTSQTPHGQTPKMDLKKHP 700
            :||..|:.||.|.||||||||||||||||.||||||.|||||||||||||||..|....|.:|:|
  Rat   639 KHQHLYRLAMTGAGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELFDFEKNP 703

  Fly   701 NCISAGGGFGPVADDGYGVSYIIAGENLIFFHISAKTTCQQTDVHRFAQNISQALSDIRSMF 762
            :.:|.||||||||||||||||||.|||.|.||||:|.:..:||.|||.:::.||:.||.::|
  Rat   704 DYVSCGGGFGPVADDGYGVSYIIVGENFIHFHISSKFSSPETDSHRFGKHLRQAMMDIITLF 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
whd	NP_001163111.1	CPT_N	1..47	CDD:465132	23/45 (51%)
		Carn_acyltransf	174..753	CDD:459926	319/581 (55%)
Cpt1a	NP_113747.2	CPT_N	1..47	CDD:465132	23/45 (51%)
		Carn_acyltransf	174..756	CDD:459926	319/581 (55%)