Protein Alignment whd and Cpt1b

DIOPT Version :10

• Sequence 1: NP_001163111.1
• Gene: whd / 36109
• FlyBaseID: FBgn0261862
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: XP_006242242.1
• Gene: Cpt1b / 25756
• RGDID: 2397
• Length: 775
• Species: Rattus norvegicus
• Alignment Length: 774
• Identity: 388/774 - (50%)
• Similarity: 511/774 - (66%)
• Gaps: 16/774 - (2%)

  Fly     1 MAEAHAAVAFSFAITHEGFDINYDHEVLNLVWNSGVRSWKKRLARARNGVRNGVYPAHIQSLWLI 65
            |||||.||||.|.:|.:|.|.....|.|..::.||:.||||||.|.:||:..||||....| ||:
  Rat     1 MAEAHQAVAFQFTVTPDGVDFRLSREALRHIYLSGINSWKKRLIRIKNGILRGVYPGSPTS-WLV 64

  Fly    66 SAIA-LGLHFAGYQAPFNLTNRILVHLPS--NTINWQVTACFLAALV----VWLSICFTMRYTLK 123
            ..:| :|.::........|.:.|...||:  .:.....|...|:.::    ||.:..|..|.|||
  Rat    65 VVMATVGSNYCKVDISMGLVHCIQRCLPTRYGSYGTPQTETLLSMVIFSTGVWATGIFLFRQTLK 129

  Fly   124 LLLMYKGWMYESRAPGSRVSLPTMLWVAVVRVLSSWNKPGLYSFQGSLPRLPLPSVKDTMTRYLR 188
            |||.|.|||:|..   |:.|..|.:|...||:||| .:|.|||||.|||:||:|||..|:.|||.
  Rat   130 LLLSYHGWMFEMH---SKTSHATKIWAICVRLLSS-RRPMLYSFQTSLPKLPVPSVPATIHRYLD 190

  Fly   189 SVRPLLDDENYTRMERLAKEFEQTIGKKLQWYLILKSWWSTNYVSDWWEEYVYLRGRSPLCVNSN 253
            |||||||||.|.|||.|||||:..|..:||.||:|||||:|||||||||||||||||||:.||||
  Rat   191 SVRPLLDDEAYFRMESLAKEFQDKIAPRLQKYLVLKSWWATNYVSDWWEEYVYLRGRSPIMVNSN 255

  Fly   254 FYGTDAIFMNLTDKQAARAANVISLLLNFRRLIEHQELQPIMVQGMIPLCSWQYERTFNTARVPG 318
            :|..|.:.:..|.:||||..|.:..::.:||.::.:|::|:|..||:|:||:|.||.|||.|:||
  Rat   256 YYAMDFVLIKNTSQQAARLGNTVHAMIMYRRKLDREEIKPVMALGMVPMCSYQMERMFNTTRIPG 320

  Fly   319 LETDRIIHYRDSNHIVVLHKGCYYKMLIYYKGRILRPCELQVQIEEILKGKATPVEGEEHLAALT 383
            .|||.:.|..:|.|:.|.|||.::|:.:|....:|:|.:|::|.:.||...:.|..|||.|||||
  Rat   321 KETDLLQHLSESRHVAVYHKGRFFKVWLYEGSCLLKPRDLEMQFQRILDDTSPPQPGEEKLAALT 385

  Fly   384 AWNRSKWAEARNTFFSWGVNQTSLRTIESAAFVLSLDDEPFEFDLARPELLDNFGKKLLHGNGYN 448
            |..|.:|||||..|||.|.|:.||.|||.|||.::||::...::......|..:||.|||||.||
  Rat   386 AGGRVEWAEARQKFFSSGKNKMSLDTIERAAFFVALDEDSHCYNPDDEASLSLYGKSLLHGNCYN 450

  Fly   449 RWFDKCFTVCVGTNGRVGFNAEHTWSDAAIASHMWENLIVDDLVSDGYDETGNTKGTPAFQPPTP 513
            |||||.||:....||::|.|.||:|:||.|..|:||.::..|....||.|||:..|.|..:.|.|
  Rat   451 RWFDKSFTLISCKNGQLGLNTEHSWADAPIIGHLWEFVLATDTFHLGYTETGHCVGEPNTKLPPP 515

  Fly   514 TRLTWDL-KPCLAQIEEATIDVTKLINEVNLRILVHQDYGKGFMKKCRISPDAYIQMALQLAYYR 577
            .|:.||: :.|...||.:......|.::|.|.......:|||.:||||.||||::|:|||||::|
  Rat   516 QRMQWDIPEQCQTAIENSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFR 580

  Fly   578 DAGRFSLTYEASMTRLFREGRTETVRPCTIESSAWVKAMQNPNTTNDERVKMMQAACDRHQLGYQ 642
            |.|:|.|||||||||:||||||||||.||.||:|:|:||...:....:...:.:.|.::||..|:
  Rat   581 DKGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKASEKHQNMYR 645

  Fly   643 DAMCGRGIDRHLFCLYVVSKYLEVDSPFLNEVLSEPWRLSTSQTPHGQTPKMDLKKHPNCISAGG 707
            .||.|.||||||||||:|||||.|.||||:|||||||.|||||.|..|....|.|::||.:.|||
  Rat   646 LAMTGAGIDRHLFCLYIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQFQICMFDPKQYPNHLGAGG 710

  Fly   708 GFGPVADDGYGVSYIIAGENLIFFHISAKTTCQQT---DVHRFAQNISQALSDIRSMFE 763
            |||||||.||||||:|||||.:|||:|:|.:..:|   :..||..:|.|||.||..:|:
  Rat   711 GFGPVADHGYGVSYMIAGENTMFFHVSSKLSSSETFPQNALRFGNHIRQALLDIADLFK 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
whd	NP_001163111.1	CPT_N	1..47	CDD:465132	24/45 (53%)
		Carn_acyltransf	174..753	CDD:459926	308/582 (53%)
Cpt1b	XP_006242242.1	CPT_N	1..47	CDD:465132	24/45 (53%)
		Carn_acyltransf	176..759	CDD:459926	308/582 (53%)