Protein Alignment whd and cpt-3

DIOPT Version :10

• Sequence 1: NP_001163111.1
• Gene: whd / 36109
• FlyBaseID: FBgn0261862
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_497498.2
• Gene: cpt-3 / 190055
• WormBaseID: WBGene00021703
• Length: 722
• Species: Caenorhabditis elegans
• Alignment Length: 742
• Identity: 228/742 - (30%)
• Similarity: 370/742 - (49%)
• Gaps: 63/742 - (8%)

  Fly    42 RLARAR----NGVRNGVYPAHIQSLWLISAIALGLHFAGYQAPFNLTNRILVHLPSNTINWQVTA 102
            ||.|.|    |.:.|.::|  ::.::.::.:||   ..||..|.:|
 Worm    23 RLERFRYRTYNFLENRLWP--VRPIYFLALVAL---ITGYGFPQDL------------------- 63

  Fly   103 CFLAALVVWLSICFTMRYTLK-LLLMYKGWMYESRAPGSRVSLPTMLWVAVVRVLSSWNKPGLYS 166
              |.:..:..|:.|.:|:.|| ....|||::.||   ..:.|..|::|..|.::||....|.|.|
 Worm    64 --LKSFFISYSLVFLLRHILKYTYFSYKGYLKES---PKKPSYATIVWGTVKKILSHVAPPQLSS 123

  Fly   167 FQGSLPRLPLPSVKDTMTRYLRSVRPLLDDENYTRMERLAKEFEQTIGKKLQWYLILKSWWSTNY 231
            ....|..||||.::||:|||..|::.::.:|.:..:...:.:|....|:.||.:..|....:.||
 Worm   124 CDRLLSNLPLPRLEDTVTRYTDSMKFVISEEEHNNLIATSTQFLSHEGRTLQRFAWLLHLITDNY 188

  Fly   232 VSDWWEEYVYLRGRSPLCVNSN-----FYGTDAIFMNLTDKQAARAANVISLLLNFRRLIEHQEL 291
            |:.:||:|:|..||.||.:.|:     .||.|    :||..........|..|.|..  ::.|:
 Worm   189 VTWFWEKYIYYAGRYPLPIISSTCQCVLYGED----DLTQVYQVARLLYIETLANLS--VDRQD- 246

  Fly   292 QPIMVQGMIPLCSWQYERTFNTARVPGLETDRIIHYRDSNHIVVLHKGCYYKM-LIYYKGRILRP 355
              .:..|...:.:..|...:|.:||||.|.|.......|.|.:|:|||.:||: .....||:...
 Worm   247 --YLAVGDGLMSTRHYRNIYNGSRVPGAEIDNFQWNPPSRHALVVHKGTWYKVDTCDEDGRLYSV 309

  Fly   356 CELQVQIEEIL--KGKATPVEGEEHLAALTAWNRSKWAEARNTFF-SWGVNQTSLRTIESAAFVL 417
            .||...:.|:.  :.|:|....:  :::|||..|::|::.|..|| :...|:..|..||::.:|:
 Worm   310 NELAKIVSELTTRQDKSTGFLCK--ISSLTADRRTEWSKNRRKFFLNNAHNKKLLEVIETSQYVI 372

  Fly   418 SLDDEPFEFDLARPELLDNFGKKLLHGNGYNRWFDKCFTVCVGTNGRVGFNAEHTWSDAAIASHM 482
            |:|..  ::.:...:.:..:.|.:|.|:|.||||||.....:..|||.|...||:.:|.|...|:
 Worm   373 SMDTA--KWGVETSDKMSVYMKDMLAGDGTNRWFDKTMNYAICANGRGGATGEHSPADGAEMDHV 435

  Fly   483 WENLIVDD---LVSDGYDETGNTK--GTPAFQPPTPTRLTWDLKPCLAQIEEATIDV-TKLINEV 541
            .||.:..|   |.|...:|.....  ..|:.......:|.::::..|.:..|...:. ||.:.::
 Worm   436 CENFLNLDKQILKSPSKEEQLEIAKLDEPSNYLKLAEKLEFEVEEGLEEEVERCYEAHTKAVADL 500

  Fly   542 NLRILVHQDYGKGFMKKCRISPDAYIQMALQLAYYRDAGRFSLTYEASMTRLFREGRTETVRPCT 606
            ::..::..|:|||.:|||.||||.::|||:||||:.|.|:|:.|||....|.:...|||||||.|
 Worm   501 HVHSIIFLDFGKGRLKKCGISPDGFVQMAIQLAYFEDQGKFTQTYETGSIRFYANSRTETVRPVT 565

  Fly   607 IESSAWVKAMQNPNTTNDERVKMMQAACDRHQLGYQDAMCGRGIDRHLFCLYVVSKYLEVDSPFL 671
            ..|...|.||.:..::...|.::::.||:.|....::.|.|.|.|||||.|.|::|.|..:||||
 Worm   566 SASCKLVCAMLDETSSKQTRRQLLKEACEVHVNNCKEVMLGNGFDRHLFVLCVIAKGLGYNSPFL 630

  Fly   672 NEVLSEPWRLSTSQTPHGQTPKMDLKKHPNCISAGGGFGPVADDGYGVSYIIAGENLIFFHISAK 736
            :...|:.|.||||..|: .|..:......|.|..||.||.||.||||:.|...|.:.|..||::.
 Worm   631 DFFSSQKWLLSTSNIPN-MTNSIAEDTSVNNIMLGGSFGAVAQDGYGICYRFGGNHAILVHITSY 694

  Fly   737 TTCQQTDVHRFAQNISQALSDIRSMFE 763
            .:.:.||..|....:..|...:..:|:
 Worm   695 HSSELTDSERIGNRLKSAFHRLAGLFD 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
whd	NP_001163111.1	CPT_N	1..47	CDD:465132	3/4 (75%)
		Carn_acyltransf	174..753	CDD:459926	192/593 (32%)
cpt-3	NP_497498.2	Carn_acyltransf	131..711	CDD:459926	192/593 (32%)