Protein Alignment whd and CRAT

DIOPT Version :10

• Sequence 1: NP_001163111.1
• Gene: whd / 36109
• FlyBaseID: FBgn0261862
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001333475.2
• Gene: CRAT / 1384
• HGNCID: 2342
• Length: 627
• Species: Homo sapiens
• Alignment Length: 626
• Identity: 187/626 - (29%)
• Similarity: 335/626 - (53%)
• Gaps: 64/626 - (10%)

  Fly   168 QGSLPRLPLPSVKDTMTRYLRSVRPLLDDENYTRMERLAKEFEQT--IGKKLQWYLILKSWWSTN 230
            |.:|||||:|.::.::..||::::|::.:|.:...::|..||:.:  :|::||..|..::..:.|
Human    33 QDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKTEN 97

  Fly   231 YVSDWWEEYVYLRGRSPLCVNSNFYGTDAIFMNLTD-----KQAARAANVISLLLNFRRLIEHQE 290
            ::|:||.:..||:.|.|:.:    |.:..:.:...|     .|...||.:|..:|:|:.:|:::.
Human    98 WLSEWWLKTAYLQYRQPVVI----YSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNET 158

  Fly   291 LQPIMVQGMIPLCSWQYERTFNTARVPGLETDRIIHY----RDSNHIVVLHKGCYYKMLIYYK-G 350
            | |:...|..|||..||.:..::.||||.:.|.:.::    :...||.|:|...::::.:|:. |
Human   159 L-PVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDG 222

  Fly   351 RILRPCELQVQIEEILKGKATPVEGEEHLAALTAWNRSKWAEARNTFFSWGVNQTSLRTIESAAF 415
            ..|...::.||:|:|......  ..:|.:..||:.:|:.||:|.||.....||:.|:|:|:.:.|
Human   223 TPLTADQIFVQLEKIWNSSLQ--TNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIF 285

  Fly   416 VLSLDDEPFEFDLARPELLDNFGK-----KLLHGNGY-----NRWFDKCFTVCVGTNGRVGFNAE 470
            .:.|       |...|.:.::..:     ::|||.|.     ||||||.....|..:|..|...|
Human   286 TVCL-------DATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYE 343

  Fly   471 HTWSDAAIASHMWENLIVDDLVSDGYDETGNTKGTPAFQPPTPTRLTWDLKPCL-AQIEEATIDV 534
            |..::......:.:.:|       .|.:......:|....|.|.:|.:::.|.: :.||:|..::
Human   344 HAAAEGPPIVTLLDYVI-------EYTKKPELVRSPLVPLPMPKKLRFNITPEIKSDIEKAKQNL 401

  Fly   535 TKLINEVNLRILVHQDYGKGFMKKCRISPDAYIQMALQLAYYRDAGRFSLTYEASMTRLFREGRT 599
            :.:|.::::.::|...:||.|.|..::||||:|||||||||||..|:...|||::..|:|..|||
Human   402 SIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRT 466

  Fly   600 ETVRPCTIESSAWVKAMQNPNTTNDERVKMMQAACDRHQLGYQD-AMCGRGIDRHL--FCLYVVS 661
            :|:|..:::|..:||||.:.:.|..::|::::.|...|: ||.| |:.|...||||  ..|..:.
Human   467 DTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHR-GYTDRAIRGEAFDRHLLGLKLQAIE 530

  Fly   662 KYLEVDSPFLNE--VLSEPWRLSTSQTPHGQTPKMDLKKHPNCISAGGGFGPVADDGYGVSYIIA 724
            ..:.:...|::.  .::..:.|||||.|    .|.|      |:..   ||||..|||||.| ..
Human   531 DLVSMPDIFMDTSYAIAMHFHLSTSQVP----AKTD------CVMF---FGPVVPDGYGVCY-NP 581

  Fly   725 GENLIFFHISAKTTCQQTDVHRFAQNISQALSDIRSMFEQH 765
            .|..|.|.:||..:|.:|:..|.|..:.:||.|:|::.:.|
Human   582 MEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSH 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
whd	NP_001163111.1	CPT_N	1..47	CDD:465132
		Carn_acyltransf	174..753	CDD:459926	178/606 (29%)
CRAT	NP_001333475.2	Carn_acyltransf	39..610	CDD:459926	178/606 (29%)