Protein Alignment whd and Crat

DIOPT Version :10

• Sequence 1: NP_001163111.1
• Gene: whd / 36109
• FlyBaseID: FBgn0261862
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001407005.1
• Gene: Crat / 12908
• MGIID: 109501
• Length: 631
• Species: Mus musculus
• Alignment Length: 634
• Identity: 185/634 - (29%)
• Similarity: 331/634 - (52%)
• Gaps: 75/634 - (11%)

  Fly   168 QGSLPRLPLPSVKDTMTRYLRSVRPLLDDENYTRMERLAKEFEQT--IGKKLQWYLILKSWWSTN 230
            |.:|||||:|.::.::..||::::|::.:|.:...::|..||:.:  :|::||..|..::....|
Mouse    32 QDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMEN 96

  Fly   231 YVSDWWEEYVYLRGRSPLCVNSNFYGTDAIFMNLTD-----KQAARAANVISLLLNFRRLIEHQE 290
            ::|:||.:..||:.|.|:.:    |.:..:.:...|     .|...||.:|..:|:|:.:|:::.
Mouse    97 WLSEWWLKTAYLQFRQPVVI----YSSPGVILPKQDFVDLQGQLRFAAKLIEGVLDFKSMIDNET 157

  Fly   291 LQPIMVQGMIPLCSWQYERTFNTARVPGLETDRIIHY----RDSNHIVVLHKGCYYKMLIYYK-G 350
            | |:...|..|||..||.:..::.||||.:.|.::::    |...||.|:|...::::.:|:. |
Mouse   158 L-PVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNYQFFELDVYHSDG 221

  Fly   351 RILRPCELQVQIEEILKGKATPVEGEEHLAALTAWNRSKWAEARNTFFSWGVNQTSLRTIESAAF 415
            ..|...::.||:|:|......  ..:|.:..||:.:|:.||:|.|......||:.|:.:|:.:.|
Mouse   222 TPLTSDQIFVQLEKIWNSSLQ--SNKEPVGILTSNHRNTWAKAYNNLIKDKVNRESVNSIQKSIF 284

  Fly   416 VLSLDDEPFEFDLARPELLDNFGK-----KLLHGNGY-----NRWFDKCFTVCVGTNGRVGFNAE 470
            .:.||.:.       |.:.|:..:     ::|||.|.     ||||||.....|..:|..|...|
Mouse   285 TVCLDKQV-------PRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYE 342

  Fly   471 HTWSD----AAIASHMWENLIVDDLVSDGYDETGNTKGTPAFQPPTPTRLTWDLKPCLA-QIEEA 530
            |..::    .|:..|:.|.....:||.           :|....|.|.:|.:::.|.:. .||:|
Mouse   343 HAAAEGPPIVALVDHVMEYTKKPELVR-----------SPMVPLPMPKKLRFNITPEIKNDIEKA 396

  Fly   531 TIDVTKLINEVNLRILVHQDYGKGFMKKCRISPDAYIQMALQLAYYRDAGRFSLTYEASMTRLFR 595
            ..:::.:|.::::.:|....:||.|.|..::||||:||:||||||||..|:...|||::..|:|.
Mouse   397 KQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASLRMFH 461

  Fly   596 EGRTETVRPCTIESSAWVKAMQNPNTTNDERVKMMQAACDRH-----QLGYQDAMCGRGIDRHL- 654
            .|||:|:|..:|:|.|:||.|.:......::|::::.|...|     ::.:..|:.|...||||
Mouse   462 LGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRISHPQAIRGEAFDRHLL 526

  Fly   655 -FCLYVVSKYLEVDSPFLNE--VLSEPWRLSTSQTPHGQTPKMDLKKHPNCISAGGGFGPVADDG 716
             ..|..:...:.:...|::.  .::..:.|||||.|    .|.|      |:..   ||||..||
Mouse   527 GLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVP----AKTD------CVMF---FGPVVPDG 578

  Fly   717 YGVSYIIAGENLIFFHISAKTTCQQTDVHRFAQNISQALSDIRSMFEQH 765
            ||:.| ...|..|.|.:||..:|.:|:..|.|..:.:||.|:|::.:.|
Mouse   579 YGICY-NPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNH 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
whd	NP_001163111.1	CPT_N	1..47	CDD:465132
		Carn_acyltransf	174..753	CDD:459926	176/614 (29%)
Crat	NP_001407005.1	Carn_acyltransf	38..614	CDD:459926	176/614 (29%)
		Microbody targeting signal. /evidence=ECO:0000255	629..631