DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11777 and PPIL4

DIOPT Version :9

Sequence 1:	NP_724939.1	Gene:	CG11777 / 36108	FlyBaseID:	FBgn0033527	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_624311.1	Gene:	PPIL4 / 85313	HGNCID:	15702	Length:	492	Species:	Homo sapiens

Alignment Length:	167	Identity:	70/167 - (41%)
Similarity:	104/167 - (62%)	Gaps:	11/167 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVTLHTDVGDLKIELFCDACPKACENFLALCASDYYSGCVFIRNI-KGFIVQTGDPTNTGKNGQ 64
            |:|.|.|.:||:.|:|:.:..|:||.|||.||...||:.|: |.|: :.||:||||||.||:.|:
Human     1 MAVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCL-IHNVQRDFIIQTGDPTGTGRGGE 64

  Fly    65 SIWGQKFDDE--FKET-----IKHTDRGMVSMANNGPNANASQFFITYAAQPN-LDLKYTLFGRV 121
            ||:||.:.|:  |.|.     |||..:|.|||.|||.:.:.|||.||.....: ||..:|:||.|
Human    65 SIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLDGVHTVFGEV 129

  Fly   122 IDGFDALDELEKLPVNPKNYRPHVDKKINGVTIHANP 158
            .:|.|.:.::.:..|: |::.|:.|.:||...|..:|
Human   130 TEGMDIIKKINETFVD-KDFVPYQDIRINHTVILDDP 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11777	NP_724939.1	Cyclophilin_PPIL3_like	1..154	CDD:238909	68/161 (42%)
PPIL4	NP_624311.1	cyclophilin_RRM	4..161	CDD:238902	66/158 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	167..188
		RRM_PPIL4	237..319	CDD:240681
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	368..406
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	423..492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810