DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11777 and Ppie

DIOPT Version :9

Sequence 1:	NP_724939.1	Gene:	CG11777 / 36108	FlyBaseID:	FBgn0033527	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_062362.1	Gene:	Ppie / 56031	MGIID:	1917118	Length:	301	Species:	Mus musculus

Alignment Length:	127	Identity:	56/127 - (44%)
Similarity:	75/127 - (59%)	Gaps:	5/127 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GDLKIELFCDACPKACENFLALCASDY---YSGCVFIRNIKGFIVQTGDPTN-TGKNGQSIWGQK 70
            |.:::.|..|..|...|||..||..:.   :.|..|.|.|..|:.|.||.|| .|..|:||:|:|
Mouse   154 GRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKK 218

  Fly    71 FDDEFKETIKHTDRGMVSMANNGPNANASQFFITYAAQPNLDLKYTLFGRVIDGFDALDELE 132
            |||| ...:|||..|::||||:|||.|.||||:|......||.|:.:||.|.:|.|.|.::|
Mouse   219 FDDE-NFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIE 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11777	NP_724939.1	Cyclophilin_PPIL3_like	1..154	CDD:238909	56/127 (44%)
Ppie	NP_062362.1	RRM	<5..194	CDD:223796	12/39 (31%)
		RRM_PPIE	8..80	CDD:240793
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	110..141
		cyclophilin_ABH_like	140..298	CDD:238907	56/127 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900