DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11777 and PPIB

DIOPT Version :9

Sequence 1:	NP_724939.1	Gene:	CG11777 / 36108	FlyBaseID:	FBgn0033527	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_000933.1	Gene:	PPIB / 5479	HGNCID:	9255	Length:	216	Species:	Homo sapiens

Alignment Length:	152	Identity:	59/152 - (38%)
Similarity:	83/152 - (54%)	Gaps:	13/152 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DVGDLKIELFCDACPKACENFLALCASDY---YSGCVFIRNIKGFIVQTGDPT-NTGKNGQSIWG 68
            |||.:...||....||..:||:||...:.   |....|.|.||.|::|.||.| ..|..|:||:|
Human    56 DVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYG 120

  Fly    69 QKFDDE-FKETIKHTDRGMVSMANNGPNANASQFFITYAAQPNLDLKYTLFGRVIDGFDALDELE 132
            ::|.|| ||  :||...|.|||||.|.:.|.||||||......||.|:.:||:|::|.:.:.::|
Human   121 ERFPDENFK--LKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVE 183

  Fly   133 KLPVNPKNYRPHVDKKINGVTI 154
            ....:.:      ||.:..|.|
Human   184 STKTDSR------DKPLKDVII 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11777	NP_724939.1	Cyclophilin_PPIL3_like	1..154	CDD:238909	58/150 (39%)
PPIB	NP_000933.1	cyclophilin_ABH_like	45..203	CDD:238907	59/152 (39%)
PPIB	NP_000933.1	Prevents secretion from ER	213..216
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810