DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11777 and PPIL3

DIOPT Version :9

Sequence 1:	NP_724939.1	Gene:	CG11777 / 36108	FlyBaseID:	FBgn0033527	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_115861.1	Gene:	PPIL3 / 53938	HGNCID:	9262	Length:	165	Species:	Homo sapiens

Alignment Length:	173	Identity:	93/173 - (53%)
Similarity:	112/173 - (64%)	Gaps:	22/173 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVTLHTDVGDLKIELFCDACPKACENFLALCASDYYSGCVFIRNIKGFIVQTGDP--------- 56
            |||||||||||:|||:||:..||.||         ..|.||....::...:.:..|
Human     1 MSVTLHTDVGDIKIEVFCERTPKTCE---------MESRCVPQAGVQWRDLGSLQPPPPGFKQVF 56

  Fly    57 ----TNTGKNGQSIWGQKFDDEFKETIKHTDRGMVSMANNGPNANASQFFITYAAQPNLDLKYTL 117
                ..||:.|.||||:||:||:.|.:||..||:|||||||||.|.|||||||..||:||:|||:
Human    57 CLSLPRTGRGGNSIWGKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTV 121

  Fly   118 FGRVIDGFDALDELEKLPVNPKNYRPHVDKKINGVTIHANPLA 160
            ||:||||.:.||||||||||.|.|||..|..|..:||||||.|
Human   122 FGKVIDGLETLDELEKLPVNEKTYRPLNDVHIKDITIHANPFA 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11777	NP_724939.1	Cyclophilin_PPIL3_like	1..154	CDD:238909	86/165 (52%)
PPIL3	NP_115861.1	cyclophilin	1..158	CDD:294131	86/165 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	237	1.000	Domainoid score	I2328
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41717
Inparanoid	1	1.050	253	1.000	Inparanoid score	I3214
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54802
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	1	1.000	-	-		oto89612
orthoMCL	1	0.900	-	-		OOG6_102733
Panther	1	1.100	-	-	LDO	PTHR45625
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R964
SonicParanoid	1	1.000	-	-		X3671
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870