DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11777 and Ppib

DIOPT Version :9

Sequence 1:	NP_724939.1	Gene:	CG11777 / 36108	FlyBaseID:	FBgn0033527	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_035279.2	Gene:	Ppib / 19035	MGIID:	97750	Length:	216	Species:	Mus musculus

Alignment Length:	151	Identity:	59/151 - (39%)
Similarity:	82/151 - (54%)	Gaps:	13/151 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VGDLKIELFCDACPKACENFLALCASDY---YSGCVFIRNIKGFIVQTGDPT-NTGKNGQSIWGQ 69
            ||.:...||....||..:||:||...:.   |....|.|.||.|::|.||.| ..|..|:||:|:
Mouse    57 VGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGE 121

  Fly    70 KFDDE-FKETIKHTDRGMVSMANNGPNANASQFFITYAAQPNLDLKYTLFGRVIDGFDALDELEK 133
            :|.|| ||  :||...|.|||||.|.:.|.||||||......||.|:.:||:|::|.|.:.::|.
Mouse   122 RFPDENFK--LKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVES 184

  Fly   134 LPVNPKNYRPHVDKKINGVTI 154
            ...:.:      ||.:..|.|
Mouse   185 TKTDSR------DKPLKDVII 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11777	NP_724939.1	Cyclophilin_PPIL3_like	1..154	CDD:238909	58/149 (39%)
Ppib	NP_035279.2	cyclophilin_ABH_like	45..203	CDD:238907	59/151 (39%)
Ppib	NP_035279.2	Prevents secretion from ER. /evidence=ECO:0000250	213..216
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810