Protein Alignment Caf1-105 and Hira

DIOPT Version :10

• Sequence 1: NP_610589.2
• Gene: Caf1-105 / 36107
• FlyBaseID: FBgn0033526
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: XP_063126748.1
• Gene: Hira / 363849
• RGDID: 1584950
• Length: 1033
• Species: Rattus norvegicus
• Alignment Length: 749
• Identity: 172/749 - (22%)
• Similarity: 307/749 - (40%)
• Gaps: 161/749 - (21%)

  Fly    15 PVLSVDIQQNGLGLRSPTICRLASGG---SDAHVLIWYVN---RSDDAEGVDV-ELAADLSRHQR 72
            |:.||||..:|        .:.|:||   ....|:||.::   :.||.:..:: ::...:..|..
  Rat    33 PIFSVDIHPDG--------TKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLA 89

  Fly    73 AVNAVRWSPNGELLASGDDESVVFIWKQKADHEVVNIVDADGCSEQDKEVWLTLKVLRGHREDIY 137
            .||.||||.:|..||||.|:.::.:|| :|.:...:.|........:.|.|..:.:||.|..|:.
  Rat    90 CVNCVRWSNSGMYLASGGDDKLIMVWK-RATYIGPSTVFGSSGKLANVEQWRCVSILRSHSGDVM 153

  Fly   138 DLSWAPNSQFLVSGSVDNTAMLWD-VHSGKSLAILDDHKGYVQGVAWDPCNQYIATMSTDRQMRI 201
            |::|:|:..:|.|.|||||.::|: |...:.||.|..|.|.|:|:.|||..:|||:.:.||.:::
  Rat   154 DVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKV 218

  Fly   202 FDANTKRVLHRVSKCVLPVKEDHEMHGKSMRLYQDGTLQTFFRRLCFTPDGKLLLTPSGITDYDG 266
            :     |.|            |.::.....:.:.:....|...||.::|||..|::...:.:...
  Rat   219 W-----RTL------------DWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGP 266

  Fly   267 VVKPI-----NTSYGFSRHDLSKPAFVLPFPKEYAVAVRCSPVLYRLRPYNAEKNPPIISLPYRM 326
            ..:.|     .|:..|..|            ::....|:.:|.:::.:..|.....|  |.|| .
  Rat   267 TAQIIEREGWKTNMDFVGH------------RKAVTVVKFNPKIFKKKQKNGSSAKP--SCPY-C 316

  Fly   327 IYAVATKN-AVFFYDTQQPVPFAIVSNIHYSRLTDLAWSSDGTVLIVSSTDGYCSLITFEPTELG 390
            ..||.:|: ::..:.|....|..::..:....:.|::|:.:|..::|.|.||..:.:.|...|||
  Rat   317 CCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELG 381

  Fly   391 DCYEDME----------TVLSVVLKSS------ENATVLKKKRQKLRKVSLDEPRKPLQEKSKPN 439
            |...:.|          ..|:::.::.      ||..:||.:|:: ::..||:.....:|.|..:
  Rat   382 DPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQ-QQQQLDQKNATTRETSSAS 445

  Fly   440 TIRRASEAGITEVGEPELDAENDSSTHSVSSN--KTNSPKTKASEEEKPTPIAIRRSPRKN-STA 501
            ::     .|:.          |..|...:..|  |.......|....:.||:.|.:....: |||
  Rat   446 SV-----TGVV----------NGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTA 495

  Fly   502 ---PMPIAIRRAPRK----------PEDKGNSE--SSKPKDEMEVTHTKTTQVQKTVASPVKRKV 551
               .:|::...|...          |.|.....  :|||         .|..|..|.|.|....|
  Rat   496 FFNSIPLSSSLAGTMLSSPSGQQLLPLDSSTPSFGASKP---------CTEPVAATSARPTGEPV 551

  Fly   552 STEAVPPAETSQPALAVIPVFEKEIISSDDKFESPEKKSRPATPIQVR---RQPRTPGSSSQFNL 613
            |.:::  ..||.|| |:.|    .::::..|.|       |......|   |...|||:.|..::
  Rat   552 SKDSM--NATSTPA-ALSP----SVLTTPSKIE-------PMKAFDSRFTERSKATPGAPSLTSV 602

  Fly   614 TPKS-QPAKQATPIAVRRT-----------------PRVLIEMPVNSPVVPMEEAMDAWPLDESI 660
            .|.: :..|:...:...|:                 |..|.:..:...|..:|:.....|
  Rat   603 IPTAVERLKEQNLVRELRSRELDSSSDSDEKVHLAKPSSLSKRKLELEVETVEKKKKGRP----- 662

  Fly   661 TPLPATKKDSRKPLPETVKTETKPAVIEASEATC 694
                  :||||. ||.::..::..|:....||.|
  Rat   663 ------RKDSRL-LPVSLSVQSPAALSAEKEAMC 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Caf1-105	NP_610589.2	WD40	<4..377	CDD:441893	95/375 (25%)
		WD40 repeat	75..131	CDD:293791	18/55 (33%)
		WD40 repeat	136..172	CDD:293791	14/36 (39%)
		WD40 repeat	179..213	CDD:293791	11/33 (33%)
		WD40 repeat	243..290	CDD:293791	10/51 (20%)
		WD40 repeat	358..382	CDD:293791	7/23 (30%)
		PHA03247	<472..742	CDD:223021	55/260 (21%)
Hira	XP_063126748.1	None