Protein Alignment Caf1-105 and chaf-2

DIOPT Version :10

• Sequence 1: NP_610589.2
• Gene: Caf1-105 / 36107
• FlyBaseID: FBgn0033526
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_490901.2
• Gene: chaf-2 / 171747
• WormBaseID: WBGene00022141
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 526
• Identity: 165/526 - (31%)
• Similarity: 250/526 - (47%)
• Gaps: 86/526 - (16%)

  Fly     5 IPEISWHNRDPVLSVDIQ---QNGLGLRSPTICRLASGG--SDAHVLIWYV--------NRSDDA 56
            :|.|.||:|..:||||:.   :||.       .|||:..  .:..|.:|..        ...::.
 Worm     5 MPIIYWHDRKGLLSVDLHHETRNGK-------YRLATASVQKEVRVRVWEFEFEMGLDPKTQENK 62

  Fly    57 EGVDVELAADLSRHQRAVNAVRWSPN--GELLASGDDESVVFIWKQKADHEVVNIVDADGCSEQD 119
            ..:.|...|:|..|..|:|.|::||:  .|||||||.|..:.||| .:|..|....|.   ...:
 Worm    63 PQLTVGFLANLVFHNHAINQVKFSPSKEHELLASGDCEGRITIWK-LSDQPVPPPQDE---MPSN 123

  Fly   120 KEVWLTLKVLRGHREDIYDLSWAPNSQFLVSGSVDNTAMLWDVHSGKSLAILDDHKGYVQGVAWD 184
            ||.|:..||| .|..|:..|.|.|:...|.|.|.|:|..:.|..:||.|.:..:.:. ..||.||
 Worm   124 KENWIRYKVL-NHNSDVNALCWDPSGTQLASVSNDHTLAVHDALTGKRLFVASNFRS-PNGVCWD 186

  Fly   185 PCNQYIATMSTDRQMRIFDANTKRVLHRVSKCVLP------VKEDHEMHGKSMRLYQDGTLQTFF 243
            |..:||||||.||:|.:.||.....|...|..:||      ...|..:..|..:|:.|..|.:|.
 Worm   187 PSGKYIATMSPDRKMDLIDAVRGARLKHFSSALLPSMTIPSANGDLHLETKIHKLFHDDQLFSFQ 251

  Fly   244 RRLCFTPDGKLLLTPS-----GITDYDGVVKPINTSYGFSRHDL---SKPAFVLPFPKEYAVAVR 300
            |.|.|:|:|:.:..|.     |.:|..|       :|.|.|.||   ..|....|.|:. ...|:
 Worm   252 RALGFSPNGEFIAAPCAHLELGSSDLYG-------TYFFRREDLGVKEAPYTFYPAPRP-TFLVK 308

  Fly   301 CSPVLYRLRPYNAEKNPPIISLPYRMIYAVATKNAVFFYDTQQPVPFAIVSNIHYSRLTDLAWSS 365
            .|||.:.|.|...|.:   :.||||:::....|:|::|||:|...|.|:|.|||.:.|||.::|.
 Worm   309 FSPVTFSLLPSTKENH---LGLPYRLLWIALNKDAIYFYDSQHSYPVAVVDNIHLNALTDASFSH 370

  Fly   366 DGTVLIVSSTDGYCSLITFEPTELGDCYEDMETVLSVVLKSSENATVLKKKRQKLRKVSLD---E 427
            ||.||:|||.:|:||.:....|:.|:       |::.::....:..::::|:||.||.::.   |
 Worm   371 DGRVLVVSSLEGFCSFVKINLTQWGE-------VMTEIVPVCGSPNLIEEKKQKKRKSTVAVVIE 428

  Fly   428 PRKPLQEKSKPNTIRRASEAGITEVGEPELDAENDSSTHSVSSNK-TNSPKT----KASEEEKPT 487
            ..|..:|.:..:.:|:.||                  |..||:.| ..:|.|    |.:..|.||
 Worm   429 KEKEKEEDAAKSPMRKPSE------------------TPKVSTPKAAGTPLTKFFKKENNTESPT 475

  Fly   488 PIAIRR 493
            |...:|
 Worm   476 PPVKKR 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Caf1-105	NP_610589.2	WD40	<4..377	CDD:441893	136/400 (34%)
		WD40 repeat	75..131	CDD:293791	24/57 (42%)
		WD40 repeat	136..172	CDD:293791	12/35 (34%)
		WD40 repeat	179..213	CDD:293791	17/33 (52%)
		WD40 repeat	243..290	CDD:293791	15/54 (28%)
		WD40 repeat	358..382	CDD:293791	14/23 (61%)
		PHA03247	<472..742	CDD:223021	9/27 (33%)
chaf-2	NP_490901.2	WD40	<27..382	CDD:441893	127/378 (34%)
		WD40 repeat	81..134	CDD:293791	24/57 (42%)
		WD40 repeat	139..178	CDD:293791	12/38 (32%)
		WD40 repeat	181..216	CDD:293791	17/34 (50%)