Protein Alignment Cyp49a1 and zgc:136333

DIOPT Version :10

• Sequence 1: NP_610588.2
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: XP_073768315.1
• Gene: zgc:136333 / 723999
• ZFINID: ZDB-GENE-060616-143
• Length: 542
• Species: Danio rerio
• Alignment Length: 471
• Identity: 141/471 - (29%)
• Similarity: 232/471 - (49%)
• Gaps: 41/471 - (8%)

  Fly   134 MNELHVN----YGKMAKV--GGLIGHPDLLFVFDGDEIRNIFKKEEAMPHRPSMPSLRHYKGDLR 192
            ::||.:.    ||.::|:  |.|.|    :.:...:.:..:.:|:|..|.|..|.....:
Zfish    95 IHELQIYQKQVYGPLSKINSGNLQG----ISISSVELLEELLRKDEKYPCRGYMTLWTEH----- 150

  Fly   193 RDFFGDVAGLIGVHGPKWEAFRQEVQHILLQPQTAKKYIPPLNDIASEFMGRIELMRD--EKDEL 255
            ||..|...|.....|.||...|..:...:|.|:.:.:|...:|.:.::|:.||..:|:  ...:|
Zfish   151 RDLRGIGYGPFTEEGEKWYKLRAVLNKRMLHPKDSLQYGDVVNAVITDFIKRIYYLREMSPTGDL 215

  Fly   256 PANFLHELYKWALESVGRVSLDTRLGCLSPEGSEEAQQIIEAINTFFWAVPELELRMPLWRIYPT 320
            .:|..:|||:::||.:..:..:||:|||..|...|.|:.|.:|...|.....:.| :|.|    |
Zfish   216 VSNLTNELYRFSLEGIASILFETRIGCLEKEIPVETQEFINSIAQMFTYSMHVAL-LPNW----T 275

  Fly   321 KAYRSF-VKALDQFTAICMKNIGKTMD-KADADEARGLSKSEADISIVERIVR--KTGNRKLAAI 381
            :.|..| .|.:|.:..| .|...|.:| |.:|.:.|..:..|.....:..::.  |..::.:...
Zfish   276 RNYFPFWQKYIDGWDGI-FKFGTKMIDMKMEAIQKRVDTNQEVAGEYLTYLLSSGKMSSKDVYGS 339

  Fly   382 LALDLFLVGVDTTSVAASSTIYQLAKNPDKQKKLFDELQKVFPHREADINQNVLEQMPYLRACVK 446
            :: :|.|.||||||......:|.|:|:|..|:.|:.|:.||.........:.| ..||:|:|.:|
Zfish   340 VS-ELLLAGVDTTSNTMLWALYLLSKDPAAQETLYQEVTKVLKDDRIPTAEEV-NSMPFLKAVIK 402

  Fly   447 ETLRMRPVVIANGRSL-QSDAVINGYHVPKGTHVIFPHLVVSNDPAYFPEPKRFLPERWLKQSTD 510
            ||||:.|||..|.|.: :::.||..|..||.|.....|..:|:|...||||::|.|||||:.
Zfish   403 ETLRLYPVVPVNSRLIAETEVVIGEYFFPKKTTFNLCHYAISHDEKVFPEPQKFKPERWLRD--- 464

  Fly   511 AAGCPHANQKIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKYKVSYNS--GEFVYRVNST 573
                  ...:.:||.|:|||||.|.|||||.||:|:|..||::.:.:::..:.  ||......|.
Zfish   465 ------GRTRPNPFGSIPFGFGVRACVGRRIAELEMHLALARLIKLFEMRPDPTVGEVKANFRSV 523

  Fly   574 YIPQSPLNFKLTLRDE 589
            .:|...:|.....|.:
Zfish   524 LVPNKKVNLHFVERQK 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp49a1	NP_610588.2	CYP24A1-like	138..581	CDD:410677	137/457 (30%)
zgc:136333	XP_073768315.1	None