Protein Alignment Cyp49a1 and cyp27c1

DIOPT Version :9

• Sequence 1: NP_001246256.1
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_001011341.1
• Gene: cyp27c1 / 496805
• XenbaseID: XB-GENE-6257635
• Length: 469
• Species: Xenopus tropicalis
• Alignment Length: 485
• Identity: 140/485 - (28%)
• Similarity: 234/485 - (48%)
• Gaps: 75/485 - (15%)

  Fly   103 VPGPYPLP-LIGNSWRFAPLIGTYKISDLDKVMNELHV-NYGKMAKVGGLIGHPDLLFVFDGDEI 165
            :|||..:. |:...||    .|..:|.::    .:.|. .||::.|  ...|...::.:.|.|.:
 Frog     1 MPGPSTMANLVEFFWR----DGFGRIQEI----QQKHARQYGRIFK--SHFGPQFVVSIADKDMV 55

  Fly   166 RNIFKKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWEAFRQEVQHILLQPQTAKKY 230
            ..:.:.|...|.|.:|.|...|     |:..|...|||...|.||...|..::..:|:|:....|
 Frog    56 AQVLRAERDAPQRANMESWHEY-----RELRGRSTGLISAEGEKWLNMRSVLRQKILRPRDVAMY 115

  Fly   231 IPPLNDIASEFMGRIELMR-DEKDELPANFLHELY-KWALESVGRVSLDTRLGCLSPEGSEEAQQ 293
            ...:|::..:.:.||..:| .|.|.|....:::|| |:::|::..:..:.|||||..:..::.::
 Frog   116 SGGVNEVVEDLVKRIRKLRVQESDGLTVTNVNDLYFKYSMEAIATILYECRLGCLDDQIPQQTKE 180

  Fly   294 IIEAINTFF---------WAVPELELRMPLW-RIYPTKAYRSFVKALD---QFTAI----CMKNI 341
            .|||:...|         .|:|:       | |....|.:|.|.::.|   :|:.|    .::.|
 Frog   181 YIEALELMFSMFKTTMYAGAIPK-------WLRPLIPKPWREFCRSWDGLFKFSQIHVDDRLRQI 238

  Fly   342 GKTMDKADADEARG-------LSKSEADISIVERIVRKTGNRKLAAILALDLFLVGVDTTSVAAS 399
            ...::|  .:|.:|       |||   ::.:.|.....|           ::.|.||||||...|
 Frog   239 ESQLEK--GEEVQGGVLTHLLLSK---ELDLEEIYANMT-----------EMLLAGVDTTSFTLS 287

  Fly   400 STIYQLAKNPDKQKKLFDELQKVFPHREADINQNVLEQMPYLRACVKETLRMRPVVIANGRSLQS 464
            ...|.|||||..|:.::.::.:.|...:....::| .:||.:||.||||||:.||:..|||..|.
 Frog   288 WATYLLAKNPGIQEAVYQQIVQNFGKDQVPTAEDV-PKMPLVRAVVKETLRLFPVLPGNGRVTQD 351

  Fly   465 DAVINGYHVPKGTHVIFPHLVVSNDPAYFPEPKRFLPERWLKQSTDAAGCPHANQKIHPFVSLPF 529
            |.|:.||.:||||.:...|...|.|...||..:.|.||||::...        .::...|.|:||
 Frog   352 DLVVGGYFIPKGTQLALCHYSTSYDAECFPAAEEFRPERWIRSGN--------LERKENFGSIPF 408

  Fly   530 GFGRRMCVGRRFAEIELHTLLAKIFRKYKV 559
            |:|.|.|:|||.||:|:|.||.::.:.:::
 Frog   409 GYGIRSCIGRRVAELEMHLLLIQLLQNFEI 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp49a1	NP_001246256.1	p450	104..565	CDD:299894	140/484 (29%)
cyp27c1	NP_001011341.1	p450	2..457	CDD:306555	140/484 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010