Protein Alignment Cyp49a1 and Cyp313a2

DIOPT Version :10

• Sequence 1: NP_610588.2
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 118/507 - (23%)
• Similarity: 208/507 - (41%)
• Gaps: 105/507 - (20%)

  Fly   102 EVPGPYPLPLIGNSWRFAPLIGTYKISDLDKVMNELHVNYGKMAKVGGLIGHPDLLFVFDGDEIR 166
            ::||...|||:|||.|:. :|...::|.....|::....|  ||    .||...::...|    .
  Fly    31 QLPGRMGLPLLGNSVRYL-IISRGRMSSRTTYMDKHGSTY--MA----WIGTTPIVITRD----P 84

  Fly   167 NIFKKEEAMP---HRPSMP--SLRHYKGDLRRDFFGDVAGLIGVHGPKWEAFRQEV----QHILL 222
            .|.:|....|   :|.|..  :|....|          .||:.:.|.||.|.|:.:    :|.:|
  Fly    85 KIAEKVLTSPFCINRSSQTTNALALSMG----------YGLLTLQGSKWMARRKHMNPAFKHSVL 139

  Fly   223 QPQTAKKYIPPLN-------DIASEFMGRIELMRDEKDELPANFLHELYKWALESVGRVSLDTRL 280
                 ..::|..|       .:...|:|     :.|||     .|.:|.:|:.    .::..|.|
  Fly   140 -----LSFLPIFNAETDLLVSVFDSFVG-----QGEKD-----VLSDLIRWSF----AIATQTTL 185

  Fly   281 GC-LSPEGSEEAQQIIEAINTFFWAVPELELRMPLWRIYPTKAYRSFVKAL-------DQFTAIC 337
            |. ::.:.:.|...|::...:.        ||:.:..|:........|..|       .:..:..
  Fly   186 GTDVTKDDNFENDAILKTYQSM--------LRLTIINIFVPFVQNKIVSKLFGLEWLRRRDASAI 242

  Fly   338 MKNIGKTMDKADADEARGLSKSEADISIVERIVRKTGNRKLAAILALDLFLVGVDTTSV------ 396
            .|.|...:||..........:||.. :::.|.:....|.:::      |..:|.:.:|:
  Fly   243 NKMINNILDKKLNSNPENYCESELK-TVIHRAIELFRNDEMS------LMELGAECSSMVLAAFE 300

  Fly   397 AASSTIYQ----LAKNPDKQKKLFDELQKVFP-HREADINQNVLEQMPYLRACVKETLRMRPVVI 456
            .::.|:|.    ||..|:.|:.:|:|:::.|| .:..::....|:|:.||...:.||||:.|.|.
  Fly   301 TSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVP 365

  Fly   457 ANGR-SLQSDAVINGYHVPKGTHVIFPHLVVSNDPAYF-PEPKRFLPERWLKQSTDAAGCPHANQ 519
            .:.| :|:...:.||..:|||..:.........:..|: .|..:|.||.:|         |....
  Fly   366 FSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFL---------PEKIH 421

  Fly   520 KIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKYKVS----YNSGEFV 567
            ..||:..:||..|:|.|:|.|:..:.....|.||.|.||:.    |.:.|||
  Fly   422 DRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFV 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp49a1	NP_610588.2	CYP24A1-like	138..581	CDD:410677	106/471 (23%)
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	106/471 (23%)