Protein Alignment Cyp49a1 and Cyp318a1

DIOPT Version :9

• Sequence 1: NP_001246256.1
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 112/501 - (22%)
• Similarity: 204/501 - (40%)
• Gaps: 92/501 - (18%)

  Fly   114 NSWRFA---PL------IGTYKISDLDKVMNELHVNYGKMAKVGGLIGHPDLLFVFDGDEIRNIF 169
            |.||..   |:      |..:..|.|:|| ::..|::.:...|  |:|...||::.|...:..:.
  Fly    33 NGWRGVIQQPVLWLLLCINLHPNSILEKV-SQYRVHFQRPLAV--LVGTRVLLYIDDPAGMECVL 94

  Fly   170 KKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWEAFRQEVQHILLQPQTAKKYIPPL 234
            ...|.:.           |..|:..||.. .||:...|.||:..|::     |.|..:...:...
  Fly    95 NAPECLD-----------KTFLQDGFFVR-RGLLHARGQKWKLRRKQ-----LNPAFSHNIVASF 142

  Fly   235 NDIASEFMGRIELMRDEKDELPANFLHELYKW--ALESVGRVSLDTRLGCLSPEGS-------EE 290
            .|:.:....::.    |:.:...|...:..|:  |.:.:.|..|:  :.||:..|:       ::
  Fly   143 FDVFNSVGNQMV----EQFQTQTNLHGQAVKFTAAEDLLSRAVLE--VSCLTIMGTPTNFTQLDD 201

  Fly   291 A------QQIIEAINTFFWAVPELELRMPLWRIYPTKAY---RSFVKALDQFTAICMKNIGKTMD 346
            |      ::::| |:......|.|::|: |.|:...:.|   :...|.|:.|....::...:...
  Fly   202 AHIAHSYKRLLE-ISAVRVVKPWLQIRL-LHRLLAPELYEESKKCAKLLEDFVGGIVRTKHRNWR 264

  Fly   347 KADADEARGLSKSEADIS-------IVERIVRKTGNRKLAAILALD----LFLVGVDTTSVAASS 400
            ..|   |.|..||..|.|       .:|:|.:...|.::.....:|    :.||..:|.|.:...
  Fly   265 LRD---AVGGEKSGEDASNGWQRRIFIEQIFQLAANGEMTLEEIMDEAQSMVLVSFETVSNSIML 326

  Fly   401 TIYQLAKNP-DKQKKLFDELQKVFPHREADINQ---NVLEQMPYLRACVKETLRMRPVVIANGRS 461
            .:..||.|. |.|::|..|::.:.|    |:.|   ..|:|:.||.|.|.|:||:...|..|.|.
  Fly   327 ALLCLATNKGDCQRRLLAEIRALVP----DVGQVGLEQLQQLRYLDAFVSESLRLLATVPMNLRH 387

  Fly   462 LQSDAVINGYH----VPKGTHVIFPHLVVSNDPAYF-PEPKRFLPERWLKQSTDAAGCPH----- 516
            :..|..:.|..    ||:.:.|:.....:..|..:: ...::|.|:|:|.|..:.....|
  Fly   388 VSRDFRLAGRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGS 452

  Fly   517 -----ANQKIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKY 557
                 ...:.|.:..|||..|.|.|:|||:....:...|.|:...:
  Fly   453 GEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNF 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp49a1	NP_001246256.1	p450	104..565	CDD:299894	112/501 (22%)
Cyp318a1	NP_727590.1	p450	42..503	CDD:299894	109/492 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100