Protein Alignment Cyp49a1 and Cyp11a1

DIOPT Version :9

• Sequence 1: NP_001246256.1
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_058982.1
• Gene: Cyp11a1 / 29680
• RGDID: 69325
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 132/538 - (24%)
• Similarity: 237/538 - (44%)
• Gaps: 84/538 - (15%)

  Fly    81 TASSLPAETTSSPAAAVRPYSEVPGPYPLPLIGNSW----RFAPLIGTYKISDLDKVMNELHVNY 141
            |.:.....:|:||    |.::|:|.|.     .|.|    .|....||::|          |.::
  Rat    31 TGNGAGISSTNSP----RSFNEIPSPG-----DNGWINLYHFLRENGTHRI----------HYHH 76

  Fly   142 -GKMAKVGGL----IGHPDLLFVFDGDEIRNIFKKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAG 201
             ....|.|.:    :|:.:.:::.|..:...:|..|...|.|..:|....|     ..::....|
  Rat    77 MQNFQKYGPIYREKLGNMESVYILDPKDAATLFSCEGPNPERYLVPPWVAY-----HQYYQRPIG 136

  Fly   202 LIGVHGPKWEAFRQEVQHILLQPQTAKKYIPPLNDIASEFMGRI--ELMRDEKDELPANFLHELY 264
            ::......|...|..:...::.|.:.|.::|.|..:|.:|:..:  .:.:....:...:...:|:
  Rat   137 VLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVLHRRIKQQNSGKFSGDISDDLF 201

  Fly   265 KWALESVGRVSLDTRLGCLSPEGSEEAQQIIEAI-NTFFWAVPELELRMPLWRIYPTKAYRS--- 325
            ::|.||:..|....|||.|......|:|:.|:|: ..|..:||.|.:...|:|::.||.::.
  Rat   202 RFAFESITSVVFGERLGMLEEIVDPESQRFIDAVYQMFHTSVPMLNMPPDLFRLFRTKTWKDHAA 266

  Fly   326 -----FVKALDQFTAICMKNIGKTMDKADADEARGLSKSEADI-SIVERIVRKTGNRKL------ 378
                 |.|| |::|    :|.     ..|..:.|..||....: |::       |..||
  Rat   267 AWDVIFSKA-DEYT----QNF-----YWDLRQKRDFSKYPGVLYSLL-------GGNKLPFKNIQ 314

  Fly   379 AAILALDLFLVGVDTTSVAASSTIYQLAKNPDKQKKLFDELQKVFPHREADINQNVLEQMPYLRA 443
            |.|  .::...||||||:.....:|::|.|...|:.|..|:.......:.|: ..:::.:|.|:|
  Rat   315 ANI--TEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVLAARRQAQGDM-AKMVQLVPLLKA 376

  Fly   444 CVKETLRMRPVVIANGRSLQSDAVINGYHVPKGTHVIFPHLVVSNDPAYFPEPKRFLPERWLKQS 508
            .:|||||:.|:.:...|.:.:|.|:..|.:|..|.|......:..:.::||.|.:|.|.|||::|
  Rat   377 SIKETLRLHPISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAMGRESSFFPNPNKFDPTRWLEKS 441

  Fly   509 TDAAGCPHANQKIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKYKVSYNSGEFV-YRVNS 572
                      |....|..|.||:|.|.|:|||.||:|:...|..:...:::...|...| .:.|.
  Rat   442 ----------QNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRIEVQSIRDVGTKFNL 496

  Fly   573 TYIPQSPL--NFKLTLRD 588
            ..:|:.|:  ||:...:|
  Rat   497 ILMPEKPIFFNFQPLKQD 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp49a1	NP_001246256.1	p450	104..565	CDD:299894	119/487 (24%)
Cyp11a1	NP_058982.1	cytochrome_P450	80..505	CDD:425388	114/459 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820