Protein Alignment Cyp49a1 and Cyp4a8

DIOPT Version :9

• Sequence 1: NP_001246256.1
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: XP_038965258.1
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 510
• Species: Rattus norvegicus
• Alignment Length: 456
• Identity: 105/456 - (23%)
• Similarity: 176/456 - (38%)
• Gaps: 129/456 - (28%)

  Fly   159 VFDGDEIRNIFKKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWEAFRQEVQHILLQ 223
            |:|.|.::.|..:.:...|. |...|..:.|          .||:.::|..|...|:     :|.
  Rat    99 VYDPDYMKLILGRSDPKSHH-SYRFLAPWIG----------YGLLLLNGQTWFQHRR-----MLT 147

  Fly   224 P----QTAKKYIPPLNDIASEFMGRIELMRDEKDELPAN------FLHELYKWALESVGRVSLDT 278
            |    .|.|.|:..:.|       .:.:|.|:.:::...      |.|         :..::|||
  Rat   148 PAFHYDTLKPYVGIMAD-------SVRIMLDKWEQIVGQDSTLEIFQH---------ITLMTLDT 196

  Fly   279 RLGC-LSPEGSEEAQQIIEAINTFFWAVPELELRMPLWRIYPTKAYRSFVKALDQFTAIC---MK 339
            .:.| .|.|||.:..                            :.|:|::||::....:.   ::
  Rat   197 IMKCAFSQEGSVQLD----------------------------RKYKSYIKAVEDLNNLSFFRIR 233

  Fly   340 NIGKTMD------------------------------KADADEARGLSKSE-------ADISIVE 367
            ||....|                              ||...:...|.|.:       .||.:..
  Rat   234 NIFHQNDIIYSLSSNGRKARSAWQLAHEHTDQVIKSRKAQLQDEEELQKVKQKRRLDFLDILLFA 298

  Fly   368 RIVR--KTGNRKLAAILALDLFLV-GVDTTSVAASSTIYQLAKNPDKQKKLFDELQKVFPHREAD 429
            ||..  ...::.|.|  .:|.|:. |.|||:...|...|.||.||:.|:....|:|.:... .|.
  Rat   299 RIENGSSLSDKDLRA--EVDTFMFEGHDTTASGISWIFYALATNPEHQQGCRKEIQSLLGD-GAS 360

  Fly   430 INQNVLEQMPYLRACVKETLRMRPVVIANGRSLQSDAVI-NGYHVPKGTHVIFPHLVVSNDPAYF 493
            |..:.|::|||...|:||.||:.|.|.|..|.|.:.... :|..:|||..|:.....:.::|..:
  Rat   361 ITWDDLDKMPYTTMCIKEALRIYPPVTAVSRMLSTPVTFPDGRSLPKGITVMLSFYGLHHNPTVW 425

  Fly   494 PEPKRFLPERWLKQSTDAAGCPHANQKIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKYK 558
            |.|:.|.|.|:         .|.:::..|.|  |||..|.|.|:|::||..||...:|....:::
  Rat   426 PNPEVFDPYRF---------APESSRHSHSF--LPFSGGARNCIGKQFAMNELKVAVALTLLRFE 479

  Fly   559 V 559
            :
  Rat   480 L 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp49a1	NP_001246256.1	p450	104..565	CDD:299894	105/456 (23%)
Cyp4a8	XP_038965258.1	CYP4B-like	72..505	CDD:410771	105/456 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000