Protein Alignment Cyp49a1 and cyp-37B1

DIOPT Version :9

• Sequence 1: NP_001246256.1
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_507109.1
• Gene: cyp-37B1 / 180093
• WormBaseID: WBGene00009226
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 517
• Identity: 136/517 - (26%)
• Similarity: 216/517 - (41%)
• Gaps: 90/517 - (17%)

  Fly   105 GPYPLPLIGNSWRFAPLIGTYKISDLDKVMNELHVNYGK--MAKVGGLIGHPDLLFVFDGDEIRN 167
            |||..|:||..:    ::..:.||.......||...|.:  ...:|..:|...|:.|.:....:.
 Worm    41 GPYSFPIIGTLY----MVNIFDISKFTTQSMELAQYYCQKGCGTIGLWLGPVPLIAVINPQHAKE 101

  Fly   168 IFKKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWEAFRQEVQHILLQPQTAKKYIP 232
            |.:..|.:........|..:.|          .||:...|.||...|:     :|.|..   :..
 Worm   102 ILESNEVITKAEEYDILFPWLG----------TGLLTSTGSKWRQRRK-----MLTPAF---HFK 148

  Fly   233 PLNDI-------ASEFMGRIELMRDEKDELPANFLHELYKWALESVGRVSLDTRLGCLSPEGSEE 290
            .|||.       |..|:.:|:...|...|:      :|:.:.......|..||.:|......:..
 Worm   149 VLNDFLSVHDYQAKVFLEQIKPYADSGKEV------DLFPYIKRLALDVICDTSMGVTIDAQNNH 207

  Fly   291 AQQIIEAIN-----TFFWAV-PELELRMPLWRIY-PTKAYRSFVKALDQFTAICMKNIGKTMDKA 348
            ..|.:|::.     .|.|.: |.|.|: |||.:. |...|...:|.:..||...:|...:...|.
 Worm   208 DHQYVESVRLLSEYAFEWILRPWLRLK-PLWYLTGPGHEYDRHLKIVTDFTKTVIKEKWEEFQKF 271

  Fly   349 DADEARGLSKSEADISIVERIVRKTGNRKLAAI-LALDL------------------FLVGVDTT 394
            ..|.                 |.||..|.:|.: |.|:|                  ...|.|||
 Worm   272 HVDP-----------------VVKTDKRSMAFLDLLLELRNEGLMNEDDIREEVDTFMFEGHDTT 319

  Fly   395 SVAASSTIYQLAKNPDKQKKLFDELQKVFPHREADINQNVLEQMPYLRACVKETLRMRPVVIANG 459
            |.:...|::.||.||:.|:|:..|:..:|...:.|...:.|:||.||..|:||:|||.|.|...|
 Worm   320 SASMGWTLWCLAHNPEFQEKVIQEVDGIFGTSDRDCTNDDLKQMKYLEKCLKESLRMYPSVPFFG 384

  Fly   460 RSLQSDAVINGYHVPKGTHVIFPHLVVSNDPAYFPEPKRFLPERWLKQSTDAAGCPHANQKIHPF 524
            |:::.|.||||...|||..:|...|::..:|..|..|.::.||.:   |.|..|..||      :
 Worm   385 RTVEQDVVINGDFFPKGVRIIVMPLLLQRNPLIFDNPNQYNPENF---SEDKIGSRHA------Y 440

  Fly   525 VSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKYKVSYNSGEFVYRVNSTYIPQSPLNFKLTL 586
            ..:||..|.|.|:|::||.:|...:::..||||:|:.:....:.::....|.:|.|.|.||:
 Worm   441 SDIPFSAGPRNCIGQKFAMMEEKAVISWFFRKYRVTASQPFGMNKILPELILKSSLGFPLTV 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp49a1	NP_001246256.1	p450	104..565	CDD:299894	130/494 (26%)
cyp-37B1	NP_507109.1	p450	41..475	CDD:278495	129/488 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4770
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860