Protein Alignment Cyp49a1 and cyp11a1

DIOPT Version :9

• Sequence 1: NP_001246256.1
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: XP_017947884.2
• Gene: cyp11a1 / 100495360
• XenbaseID: XB-GENE-960779
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 531
• Identity: 146/531 - (27%)
• Similarity: 237/531 - (44%)
• Gaps: 85/531 - (16%)

  Fly    86 PAETTSSPAAAVRPYSEVPGPYPLPLIGNSWR--FAPLIGTYKISDLDKVMNELHVNYGKMAKV- 147
            |...|.|......||:::||         :|:  :..|...::......:...:..|:.:...:
 Frog    27 PEMGTLSQVDTPLPYNQMPG---------NWKRGWLELYRFWRKDGFHNIHYHMMENFQRFGPIY 82

  Fly   148 GGLIGHPDLLFVFDGDEIRNIFKKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWEA 212
            ...:|..|.:|:...::...:|..|...|.|..:|....|     ||:.....|::...|..|.:
 Frog    83 REALGIYDSVFIQLPEDAATLFHVEGLHPERLRVPPWYEY-----RDYRNRRYGVLLKKGEDWRS 142

  Fly   213 FRQEVQHILLQPQTAKKYIPPLNDIASEFMGR--IELMRDEKDELPANFLHELYKWALESVGRVS 275
            .|..:...:|......:::|.|:.:..:|:.|  |::.|..:.:..|:..:||:::|||||..|.
 Frog   143 HRIALNREVLSMSAMSRFLPLLDSVGQDFVHRAHIQVERSGRGKWTADLTNELFRFALESVCYVL 207

  Fly   276 LDTRLGCLSPEGSEEAQQIIEAINTFF-WAVPELELRMPLWRIYPTKAYRSFVKALDQ-FTAI-- 336
            ...|||.|......|:||.|::::..| ...|.|.|...|.|...:..::..|:|.|. ||..
 Frog   208 YGQRLGLLQDYIDPESQQFIDSVSLMFNTTAPMLYLPPSLLRKINSSIWKDHVRAWDAIFTHADR 272

  Fly   337 CMKNIGKTMDKADADEARGLSKSEADISIVERIVRKTGNRKLAAILALD-------------LFL 388
            |::.|..::            :.::|         .|.:..|:::|..|             |..
 Frog   273 CIQQIYSSL------------RQQSD---------STYSGVLSSLLLQDQMPLEDIKASVTELMA 316

  Fly   389 VGVDTTSVAASSTIYQLAKNPDKQKKLFDELQKVFPHREA---DINQNVLEQMPYLRACVKETLR 450
            .||||||:.....:|:||:.|..|:||..|   |...|:|   |:.. :|:::|.::|.:|||||
 Frog   317 GGVDTTSMTLQWAMYELARTPSVQEKLRSE---VIAARDASGKDLTA-LLKRIPLVKAALKETLR 377

  Fly   451 MRPVVIANGRSLQSDAVINGYHVPKGTHVIFPHLVVSNDPAYFPEPKRFLPERWLKQSTDAAGCP 515
            :.||.|...|..|.|.||..|.:|:||.|......:..:|..|..|:||.|||||     ..|..
 Frog   378 LHPVAITLQRYTQRDTVIRNYIIPQGTLVQVGLYAMGRNPDIFALPQRFSPERWL-----GGGPT 437

  Fly   516 HANQKIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKYKVSYNSGEFVYRVNSTY----IP 576
            |       |..|.||||.|.|:|||.||||:...|..|...:|:..|.   :..|.:|:    .|
 Frog   438 H-------FRGLGFGFGPRQCIGRRIAEIEMQLFLIHILENFKIEINR---MVDVGTTFNLILFP 492

  Fly   577 QSPLNFKLTLR 587
            ..|::  ||||
 Frog   493 SKPIH--LTLR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp49a1	NP_001246256.1	p450	104..565	CDD:299894	133/485 (27%)
cyp11a1	XP_017947884.2	cytochrome_P450	75..497	CDD:425388	132/466 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9361
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2442
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950