DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphao and GP ALPHA 1

DIOPT Version :9

Sequence 1:	NP_523684.2	Gene:	Galphao / 36104	FlyBaseID:	FBgn0001122	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001325056.1	Gene:	GP ALPHA 1 / 817170	AraportID:	AT2G26300	Length:	383	Species:	Arabidopsis thaliana

Alignment Length:	393	Identity:	149/393 - (37%)
Similarity:	227/393 - (57%)	Gaps:	51/393 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MG--CAQS------AEERAAAARSRLIERNLKEDGIQAAKDI-KLLLLGAGESGKSTIVKQMKII 56
            ||  |::|      .:|...||.   |||.::::. :|.|.| |||||||||||||||.||:|::
plant     1 MGLLCSRSRHHTEDTDENTQAAE---IERRIEQEA-KAEKHIRKLLLLGAGESGKSTIFKQIKLL 61

  Fly    57 HESGFTAEDFKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKM-----------VFDV 110
            .::||...:.|.|.||:::|..|:    ::.:...:.:::.||.:|...|           :.::
plant    62 FQTGFDEGELKSYVPVIHANVYQT----IKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEI 122

  Fly   111 CQRMHDTEPFSEELLAAMKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDI 175
            ..|: |....::::...::.||:|..:||..:|.||.|:.|..||.:::|.||...:|.||::|:
plant   123 GGRL-DYPRLTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDV 186

  Fly   176 LRTRVKTTGIVEVHFSFKNLN------FKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQV 234
            |..||:|||:||:.||....|      ::||||||||:||:||||.||.|||:|||.|:|||||.
plant   187 LYARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQT 251

  Fly   235 LHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRKSPLTIC--FPEY----TG 293
            |.|||..|||.|:.:|||.:.....|..||.:|||||.|:||:|:...||.:|  |.:|    :|
plant   252 LFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSG 316

  Fly   294 GQEYGEAAAYIQAQFEA---KNKSTSK-----EIYCHMTCATDTNNIQFVFDAVTDVIIANNLRG 350
            .||...|..:::.:||.   :|.:..:     :||  .|.|.|...::..|..|.:.:...||..
plant   317 KQEIEHAYEFVKKKFEELYYQNTAPDRVDRVFKIY--RTTALDQKLVKKTFKLVDETLRRRNLLE 379

  Fly   351 CGL 353
            .||
plant   380 AGL 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	133/345 (39%)
GP ALPHA 1	NP_001325056.1	G-alpha	40..377	CDD:206639	132/343 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	229	1.000	Domainoid score	I660
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	233	1.000	Inparanoid score	I1124
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	1	1.000	-	-		otm3584
orthoMCL	1	0.900	-	-		OOG6_100285
Panther	1	1.100	-	-	LDO	PTHR10218
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840