Protein Alignment Galphao and Gna11

DIOPT Version :10

• Sequence 1: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_112295.2
• Gene: Gna11 / 81662
• RGDID: 619749
• Length: 359
• Species: Rattus norvegicus
• Alignment Length: 353
• Identity: 173/353 - (49%)
• Similarity: 235/353 - (66%)
• Gaps: 9/353 - (2%)

  Fly     1 MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAED 65
            |.|..|.|.:.:...:..||:.|:.|...|.:::||||||.|||||||.:|||:|||.:|::.||
  Rat     7 MACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEED 71

  Fly    66 FKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTE---PFSEELLAA 127
            .:.:..:||.|...::.|::|||.||.|:|...:.:::|.::.:|     |.|   .|..:.:.|
  Rat    72 KRGFTKLVYQNIFTAMQAVVRAMDTLKIRYKYEQNKANALLIREV-----DVEKVTTFEHQYVNA 131

  Fly   128 MKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSF 192
            :|.||.|.|||||:.|..|:||:|||||:|.|:||:....|.||:||:||.||.||||:|..|..
  Rat   132 IKTLWSDPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEYPFDL 196

  Fly   193 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNN 257
            :|:.|::.|||||||||:|||||||:||:|:|.||:|||||||.|.:..|||:||..||.:|...
  Rat   197 ENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITY 261

  Fly   258 KWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEAA-AYIQAQFEAKNKSTSKEIYC 321
            .||..:|:|||||||||.|:||..|.|...|||:.|.|...:|| .:|...|...|..:.|.||.
  Rat   262 PWFQHSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYS 326

  Fly   322 HMTCATDTNNIQFVFDAVTDVIIANNLR 349
            |.||||||.||:|||.||.|.|:..||:
  Rat   327 HFTCATDTENIRFVFAAVKDTILQLNLK 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	162/317 (51%)
Gna11	NP_112295.2	G-alpha	40..353	CDD:206639	162/317 (51%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	41..54		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	178..186		5/7 (71%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	201..210		5/8 (63%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	270..277		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	329..334		4/4 (100%)