DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphao and gna15.1

DIOPT Version :9

Sequence 1:	NP_523684.2	Gene:	Galphao / 36104	FlyBaseID:	FBgn0001122	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001003626.2	Gene:	gna15.1 / 445232	ZFINID:	ZDB-GENE-040801-146	Length:	367	Species:	Danio rerio

Alignment Length:	356	Identity:	162/356 - (45%)
Similarity:	226/356 - (63%)	Gaps:	7/356 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDFK 67
            |..|.|::.|......|:|.|.|...:..::||:||||.|||||:|.:|||:|||..||:.||.:
Zfish    13 CCLSEEDKNAIVIHNEIKRILAEQKKRERREIKVLLLGTGESGKTTFIKQMRIIHGKGFSEEDRR 77

  Fly    68 QYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTEPFSEELLAAMKRLW 132
            .|...||.|...::.|:..||.:|.|.|:|.:.|:..:...||  .:..........:.|::|||
Zfish    78 GYIKNVYQNIFTAMRAMTGAMESLRIPYANPQNEAYGRQFKDV--EIRQVTQLDRMYVEAIRRLW 140

  Fly   133 QDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNLNF 197
            .|.|::.|:.|..||||.||.:|::.:|||:.|.||.||.||:||.|..||||.:..||.:.:..
Zfish   141 ADPGIKACYCRRREYQLLDSTEYYMTNLDRIAAPDYIPTAQDVLRVRFPTTGINDYSFSVEKITL 205

  Fly   198 KLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTD 262
            ::.|||||:|||:|||||||:||::||..::|||||||.|:...|||:|||.||.:..::.||..
Zfish   206 RIVDVGGQKSERRKWIHCFENVTSLIFLASLSEYDQVLEENSKENRMKESLSLFYTTIHSPWFAS 270

  Fly   263 TSIILFLNKKDLFEEKIRKSPLTICFPEYTG-GQEYGEAAAYIQAQFEAKNK----STSKEIYCH 322
            .||||||||.|:.||||:.|.|...|||:.| .::..:|.:||...:|.|.|    .|||:||.|
Zfish   271 ASIILFLNKMDILEEKIQSSDLKAYFPEFQGRRRDVQDAKSYISHLYEQKAKCTETKTSKQIYPH 335

  Fly   323 MTCATDTNNIQFVFDAVTDVIIANNLRGCGL 353
            .|||||||||:.||..|.|.::..:||..|:
Zfish   336 FTCATDTNNIRKVFGDVKDTVLIRSLREYGV 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	151/318 (47%)
gna15.1	NP_001003626.2	G-alpha	44..361	CDD:206639	151/318 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.930